Hydrochloric Acid → 5-Chloro-3-fluoropyridine-2-carboxylic acid

HRID 944462

Reaction equation

HRID 944462 reaction equation
[CH3:17][S:18](=[O:19])[CH3:20].[ClH:16].[F:1][c:2]1[c:3]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[n:4][cH:5][c:6]([Cl:8])[cH:7]1.[Na+:15].[OH-:14]>>[F:1][c:2]1[c:3]([C:9](=[O:10])[OH:11])[n:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 961HydroxideHCID 22013569Ethyl 5-chloro-3-fluoropicolinate

Product 1

HCID 117690705-Chloro-3-fluoropyridine-2-carboxylic acid

Sources & evidence

ORD record
ord-27acd18fc4954594b37a11870af3f8ee
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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