Acetonitrile → 5-(3-Fluorooxetan-3-yl)isoindoline
Reaction equation
[CH2:15]([N:16]([S:17]([F:18])([F:19])[F:21])[CH2:20][CH3:22])[CH3:23].[CH2:1]1[NH:2][CH2:3][c:4]2[cH:5][c:6]([C:10]3([OH:14])[CH2:11][O:12][CH2:13]3)[cH:7][cH:8][c:9]21.[CH3:24][C:25]#[N:26].[N+:27]([CH3:28])([O-:29])=[O:30]>>[CH2:1]1[NH:2][CH2:3][c:4]2[cH:5][c:6]([C:10]3([F:21])[CH2:11][O:12][CH2:13]3)[cH:7][cH:8][c:9]21Participants
5
Sources & evidence
- ORD record
- ord-4e54648583904340b4aefc7fb0841d97
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…