Tetrahydrofuran → methyl 2-[3-(4-methoxyphenoxy)-5-oxo-2H-pyrrol-1-yl]-4-methylpentanoate

Reaction equation

[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]([CH3:7])[CH3:8])[NH:9][CH2:10][C:11](=[CH:12][C:13](=[O:14])[O:15][CH2:16][CH3:17])[O:18][c:19]1[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]1)=[O:27].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]([CH3:7])[CH3:8])[N:9]1[CH2:10][C:11]([O:18][c:19]2[cH:20][cH:21][c:22]([O:25][CH3:26])[cH:23][cH:24]2)=[CH:12][C:13]1=[O:14])=[O:27]

Participants

Reactant 2

HCID 8028Tetrahydrofuran

HCID 66895198Methyl 2-[[4-ethoxy-2-(4-methoxyphenoxy)-4-oxobut-2-enyl]amino]-4-methylpentanoate

Product 1

HCID 66893491methyl 2-[3-(4-methoxyphenoxy)-5-oxo-2H-pyrrol-1-yl]-4-methylpentanoate

Sources & evidence

ORD record: ord-af1d5f49117a45b4ae9fc93e9c3f6798
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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