N-methyl-2-pyrrolidone → 6-[3-(3-methoxypropyl)piperazin-1-yl]-8-(trifluoromethyl)-11H-benzo[b][1,4]benzodiazepine

Reaction equation

[CH3:21][O:22][CH2:23][CH2:24][CH2:25][CH:26]1[NH:27][CH2:28][CH2:29][NH:30][CH2:31]1.[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([cH:17][cH:18]1)[NH:7][c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[N:10]=[C:11]2[NH2:12])([F:19])[F:20]>>[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([cH:17][cH:18]1)[NH:7][c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[N:10]=[C:11]2[N:12]1[CH2:29][CH2:28][NH:27][CH:26]([CH2:25][CH2:24][CH2:23][O:22][CH3:21])[CH2:31]1)([F:19])[F:20]