Methyl iodide → 3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl Ester

HRID 947376Notes

Reaction equation

HRID 947376 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][c:12]1[cH:13][n:14][c:15]2[n:16]([c:17]1=[O:18])[CH:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]2.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:29][I:30]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][c:12]1[cH:13][n:14][c:15]2[n:16]([c:17]1=[O:18])[C:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH2:20][CH2:21]2

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 76136427tert-butyl 4-oxo-3-(phenylmethoxycarbonylamino)-7,8-dihydro-6H-pyrrolo[1,2-a]pyrimidine-6-carboxylate

Product 1

HCID 696008793-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl Ester

Sources & evidence

ORD record
ord-d105b852be294810a4951b4fc5bfb8af
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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