Ethanol → N-(2-chloro-3-hydroxybenzyl)piperidine

HRID 948031

Reaction equation

HRID 948031 reaction equation
[BH4-:17].[CH2:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[CH3:19][CH2:20][OH:21].[Cl:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][c:9]1[OH:10].[Na+:18]>>[Cl:1][c:2]1[c:3]([CH2:4][N:14]2[CH2:13][CH2:12][CH2:11][CH2:16][CH2:15]2)[cH:6][cH:7][cH:8][c:9]1[OH:10]

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 8082PiperidineHCID 28123BorohydrideHCID 5933762-Chloro-3-hydroxybenzaldehyde

Product 1

HCID 21294597N-(2-chloro-3-hydroxybenzyl)piperidine

Sources & evidence

ORD record
ord-d137de8dc6cd4c26b9efb591fdb324bd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…