Bromide ion → 1-Benzyl-3-phenyl-piperidin-3-ol
Reaction equation
[Br-:15].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10](=[O:14])[CH2:11][CH2:12][CH2:13]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[OH2:28].[c:16]1([Mg+:22])[cH:17][cH:18][cH:19][cH:20][cH:21]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([OH:14])([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:11][CH2:12][CH2:13]1Participants
7
Sources & evidence
- ORD record
- ord-389dc0a0afdd47e7875950f88a14a9d3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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