Dimethylacetamide → N-[3-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-4-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 950422

Reaction equation

HRID 950422 reaction equation
[CH3:25][n:26]1[n:27][c:28]([CH3:34])[cH:29][c:30]1[C:31](=[O:32])[Cl:33].[CH3:35][N:36]([CH3:37])[C:38](=[O:39])[CH3:40].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH3:24])[c:6]([O:7][c:8]2[cH:9][cH:10][c:11]3[n:12]([cH:13]2)[n:14][c:15]([NH:17][C:18](=[O:19])[CH:20]2[CH2:21][CH2:22]2)[n:16]3)[cH:23]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH3:24])[c:6]([O:7][c:8]2[cH:9][cH:10][c:11]3[n:12]([cH:13]2)[n:14][c:15]([NH:17][C:18](=[O:19])[CH:20]2[CH2:21][CH2:22]2)[n:16]3)[cH:23]1)[C:31]([c:30]1[n:26]([CH3:25])[n:27][c:28]([CH3:34])[cH:29]1)=[O:32]

Participants

4

Reactant 3

HCID 31374DimethylacetamideHCID 27362992,5-Dimethyl-2H-pyrazole-3-carbonyl chlorideHCID 57749340N-[6-(3-amino-6-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

Product 1

HCID 57749237N-[3-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-4-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

Sources & evidence

ORD record
ord-b65d404053c2486dae60941bb00e9da1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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