Phosphorus oxychloride → 1-Cyclohexyl-5-chloro-3,4-dihydroisoquinoline
Reaction equation
[CH:1]1([C:7](=[O:8])[NH:9][CH2:10][CH2:11][c:12]2[c:13]([Cl:18])[cH:14][cH:15][cH:16][cH:17]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[P:19]([Cl:20])([Cl:21])([Cl:22])=[O:23]>>[CH:1]1([C:7]2=[N:9][CH2:10][CH2:11][c:12]3[c:13]([Cl:18])[cH:14][cH:15][cH:16][c:17]32)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-157576e59dd1479f8bff9f6cfbb3ebcb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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