Potassium Cation → 8-bromo-7-(4-chlorophenyl)-2-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

HRID 952540

Reaction equation

HRID 952540 reaction equation
[Br:19][CH2:20][c:21]1[c:22]([CH3:31])[n:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]1.[Br:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]1)[c:15](=[O:18])[nH:16][n:17]2.[K+:32].[K+:33].[O-:34][C:35]([O-:36])=[O:37].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[Br:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]1)[c:15](=[O:18])[n:16]([CH2:20][c:21]1[c:22]([CH3:31])[n:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]1)[n:17]2

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 577994388-Bromo-7-(4-chlorophenyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneHCID 598348213-(Bromomethyl)-2-methyl-6-(trifluoromethyl)pyridine

Product 1

HCID 577994058-bromo-7-(4-chlorophenyl)-2-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Sources & evidence

ORD record
ord-b062f891b7e84645b4b915b336fbafb1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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