Phosphorus oxychloride → 3-Benzyl-5-chloro-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][n:10][c:11]2[c:12]([c:13]1=[O:14])[c:15]([OH:21])[cH:16][c:17](=[O:20])[n:18]2[CH3:19].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][n:10][c:11]2[c:12]([c:13]1=[O:14])[c:15]([Cl:24])[cH:16][c:17](=[O:20])[n:18]2[CH3:19]Participants
3
Sources & evidence
- ORD record
- ord-f51632acb4534d63b42cc3695982e1cb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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