Acetate → N-methyl-2-[[2-[(2-methylpyrazol-3-yl)amino]-5-(trifluoromethyl)-4-pyridyl]amino]benzamide
Reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH3:23][n:24]1[n:25][cH:26][cH:27][c:28]1[NH2:29].[CH3:36][C:37]1([CH3:38])[c:39]2[cH:40][cH:41][cH:42][c:43]([P:44]([c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[c:51]3[cH:52][cH:53][cH:54][cH:55][cH:56]3)[c:57]2[O:58][c:59]2[c:60]1[cH:61][cH:62][cH:63][c:64]2[P:65]([c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1)[c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][cH:16][cH:17][cH:18]2)[cH:7]1.[Cs+:34].[Cs+:35].[O-:85][C:86]([CH3:87])=[O:88].[O-:89][C:90]([CH3:91])=[O:92].[O:78]1[CH2:79][CH2:80][O:81][CH2:82][CH2:83]1.[Pd+2:84]>>[c:2]1([NH:29][c:28]2[n:24]([CH3:23])[n:25][cH:26][cH:27]2)[n:3][cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][cH:16][cH:17][cH:18]2)[cH:7]1Participants
9
Reactant 8
HCID 175Acetate2×
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 104967Cesium cation2×
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 1369272-Methyl-2H-pyrazol-3-ylamine
HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)
HCID 566553282-[2-Chloro-5-(trifluoromethyl)pyridin-4-ylamino]-N-methylbenzamideProduct 1
Sources & evidence
- ORD record
- ord-d0fe90a6259e44c6820b4af636087db9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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