Acetic Acid → 1-(3,4-Dichlorobenzyl)-4-(2-aminocyclohexyl)piperazine

HRID 953957

Reaction equation

HRID 953957 reaction equation
[CH3:25][C:26](=[O:27])[OH:28].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][N:9]([CH:12]3[CH:13]([N+:18]([O-:19])=[O:20])[CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[cH:21][cH:22][c:23]1[Cl:24].[Pt:29](=[O:30])=[O:31]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][N:9]([CH:12]3[CH:13]([NH2:18])[CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[cH:21][cH:22][c:23]1[Cl:24]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 345198Adams' catalystHCID 222577511-(3,4-Dichlorobenzyl)-4-(2-nitrocyclohexyl)piperazine

Product 1

HCID 222577361-(3,4-Dichlorobenzyl)-4-(2-aminocyclohexyl)piperazine

Sources & evidence

ORD record
ord-a0fc030bf1a246eb9c861af5cc9d0495
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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