1-Butanol → 2-(4-(5-Bromopyrimidin-2-ylamino)phenyl)ethanol

HRID 95408

Reaction equation

HRID 95408 reaction equation
[Br:11][c:12]1[cH:13][n:14][c:15]([Cl:18])[n:16][cH:17]1.[CH2:30]([OH:31])[CH2:32][CH2:33][CH3:34].[CH:21]([N:22]([CH:23]([CH3:24])[CH3:25])[CH2:26][CH3:27])([CH3:28])[CH3:29].[I-:20].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][OH:10])[cH:6][cH:7]1.[Na+:19].[OH2:35]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH2:8][CH2:9][OH:10])[cH:6][cH:7]1)[c:15]1[n:14][cH:13][c:12]([Br:11])[cH:17][n:16]1

Participants

8

Reactant 7

HCID 2631-ButanolHCID 923Sodium ionHCID 962WaterHCID 30165Iodide IonHCID 669044-Aminophenethyl alcoholHCID 81531DiisopropylethylamineHCID 6066655-Bromo-2-chloropyrimidine

Product 1

HCID 576326232-(4-(5-Bromopyrimidin-2-ylamino)phenyl)ethanol

Sources & evidence

ORD record
ord-8c3cc169daa34747a8df6ac3348c6e01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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