Bromoacetyl bromide → 2-Benzyl-1-(2-bromoacetylamino)-6-methylbenzene

Reaction equation

[CH2:1]([C:8]1[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[C:9]=1[NH2:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:16][CH2:17][C:18](Br)=[O:19]>>[CH2:1]([C:8]1[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[C:9]=1[NH:10][C:18](=[O:19])[CH2:17][Br:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 61147Bromoacetyl bromide

HCID 122900952-Benzyl-6-methylaniline

Product 1

HCID 196942692-Benzyl-1-(2-bromoacetylamino)-6-methylbenzene

Procedure

2-benzyl-6-methylaniline [A. W. H. Wardrop et al.: J. Chem. Soc., Perkin Trans. 1, 12, 1279 (1976)] and bromoacetyl bromide were used to produce the above compound in the same way as Reference Example 8.

Workup

customto produce the above compound in the same way as Reference Example 8

Sources & evidence

ORD record: ord-d2f33c1431d042dc8d4c42d33385b25c
Source dataset: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05723475

Reaction notes

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