Bis(4-fluorophenyl)(piperidin-4-yl)methanol → Hydrochloric Acid

HRID 957667Notes

Reaction equation

HRID 957667 reaction equation
[CH2:23]([CH3:24])[O:25][C:26]([CH2:27][c:28]1[cH:29][c:30]([O:39][CH3:40])[c:31]([O:34][CH2:35][CH2:36][CH2:37][Cl:38])[cH:32][cH:33]1)=[O:41].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:6][cH:7]1>>[ClH:38].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([CH:10]2[CH2:11][CH2:12][N:13]([CH2:37][CH2:36][CH2:35][O:34][c:31]3[c:30]([O:39][CH3:40])[cH:29][c:28]([CH2:27][C:26]([O:25][CH2:23][CH3:24])=[O:41])[cH:33][cH:32]3)[CH2:14][CH2:15]2)[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:6][cH:7]1

Participants

4

Reactant 2

HCID 11208889Bis(4-fluorophenyl)(piperidin-4-yl)methanolHCID 144071784-(3-Chloropropoxy)-3-methoxybenzeneacetic acid ethyl ester

Product 2

HCID 313Hydrochloric AcidHCID 144071074-[3-[4-[Bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]-3-methoxybenzeneacetic acid ethyl ester

Sources & evidence

ORD record
ord-0aa07d5a7ab741f883707e7282929574
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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