4-Chlorobutyryl chloride → 5-(4-Chlorobutyryl)-2,3,4,5-tetrahydro-1,5-benzoxazepine
Reaction equation
[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[NH:5][CH2:4][CH2:3][CH2:2]1.[Cl:12][CH2:13][CH2:14][CH2:15][C:16](Cl)=[O:17]>>[Cl:12][CH2:13][CH2:14][CH2:15][C:16]([N:5]1[C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[O:1][CH2:2][CH2:3][CH2:4]1)=[O:17]Participants
3
Procedure
2,3,4,5-tetrahydro-1,5-benzoxazepine and 4-chlorobutyryl chloride were used to produce the above compound in the same way as Reference Example 8.
Workup
- customto produce the above compound in the same way as Reference Example 8
Sources & evidence
- ORD record
- ord-04e4aa0d550f42b3965842045af58c87
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05723475
Reaction notes
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