Diethyl Ether → Methyl 4-[4-(4-hydroxy-4-methylpent-2-ynoxy)phenyl]sulfonyl-2,6-dimethylmorpholine-3-carboxylate

HRID 960154

Reaction equation

HRID 960154 reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH:6]([CH3:22])[O:7][CH:8]([CH3:21])[CH2:9][N:10]1[S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]1.[CH3:42][CH2:43][O:44][CH2:45][CH3:46].[Cs+:35].[Cs+:36].[I:23][CH2:24][C:25]#[C:26][C:27]([CH3:28])([OH:29])[CH3:30].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH:6]([CH3:22])[O:7][CH:8]([CH3:21])[CH2:9][N:10]1[S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([O:20][CH2:24][C:25]#[C:26][C:27]([CH3:28])([OH:29])[CH3:30])[cH:18][cH:19]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 120166895-Iodo-2-methyl-pent-3-yn-2-olHCID 187409804-(4-Hydroxy-benzenesulfonyl)-2,6-dimethyl-morpholine-3-carboxylic acid methyl ester

Product 1

HCID 18740978Methyl 4-[4-(4-hydroxy-4-methylpent-2-ynoxy)phenyl]sulfonyl-2,6-dimethylmorpholine-3-carboxylate

Sources & evidence

ORD record
ord-ba80786a07974f5093648566a855d654
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…