Potassium Cation → 2-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole

HRID 96054

Reaction equation

HRID 96054 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:18][O:19][c:20]1[cH:21][cH:22][c:23]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:24][cH:25]1.[Cl:7][CH2:8][c:9]1[nH:10][c:11]2[c:12]([n:13]1)[cH:14][cH:15][cH:16][cH:17]2.[K+:5].[K+:6].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH2:37]>>[CH2:8]([c:9]1[nH:10][c:11]2[c:12]([n:13]1)[cH:14][cH:15][cH:16][cH:17]2)[N:29]1[CH2:28][CH2:27][N:26]([c:23]2[cH:22][cH:21][c:20]([O:19][CH3:18])[cH:25][cH:24]2)[CH2:31][CH2:30]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 785712-ChloromethylbenzimidazoleHCID 2697221-(4-Methoxyphenyl)piperazine

Product 1

HCID 6676752-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole

Sources & evidence

ORD record
ord-1ba5bd2006074d809df0b8d00f28aaec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…