Piperazine → 3-Fluoro-N-[4-(3-piperazin-1-yl-propoxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide

HRID 961558

Reaction equation

HRID 961558 reaction equation
[CH2:32]1[CH2:33][NH:34][CH2:35][CH2:36][NH:37]1.[Cl:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]([NH:16][C:17]([c:18]2[cH:19][c:20]([F:30])[cH:21][c:22]([N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[cH:23]2)=[O:31])[c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]12>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[cH:7][cH:8][c:9]([NH:16][C:17]([c:18]2[cH:19][c:20]([F:30])[cH:21][c:22]([N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[cH:23]2)=[O:31])[c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]12)[N:34]1[CH2:33][CH2:32][NH:37][CH2:36][CH2:35]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 59553319N-[4-(3-chloropropoxy)-naphthalen-1-yl]-3-fluoro-5-piperidin-1-yl-benzamide

Product 1

HCID 595532773-Fluoro-N-[4-(3-piperazin-1-yl-propoxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide

Sources & evidence

ORD record
ord-2b79ec44be29428699ce54d2f6b79fba
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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