Trifluoroacetic acid → 7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:8][CH:9]1[CH2:10][N:11]([c:14]2[c:15]([F:32])[cH:16][c:17]3[c:18](=[O:31])[c:19]([C:28](=[O:29])[OH:30])[cH:20][n:21]([CH:25]4[CH2:26][CH2:27]4)[c:22]3[c:23]2[F:24])[CH2:12][CH2:13]1)[CH2:5][CH2:6][CH3:7].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH2:8][CH:9]1[CH2:10][N:11]([c:14]2[c:15]([F:32])[cH:16][c:17]3[c:18](=[O:31])[c:19]([C:28](=[O:29])[OH:30])[cH:20][n:21]([CH:25]4[CH2:26][CH2:27]4)[c:22]3[c:23]2[F:24])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-6b2dbd377d354f08a6d31395dfa82bb8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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