→ 4-(2-chlorophenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

HRID 962348

Reaction equation

HRID 962348 reaction equation
CC(=O)CC(=O)Nc1ccccc1.CC(=O)O.CCO.NC(N)=S.O.O.O.O.O.O.O.O=Cc1ccccc1Cl.[Cl-].[Cl-].[Cl-].[La+3]>>CC1=C(C(=O)Nc2ccccc2)C(c2ccccc2Cl)NC(=S)N1

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 28784574-(2-chlorophenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamideYield 89%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 702EthanolOtherHCID 69962-ChlorobenzaldehydeOtherHCID 7592AcetoacetanilideOtherHCID 165791Lanthanum chloride heptahydrateOtherHCID 2723790ThioureaOther

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. additionNo procedure recorded
  3. waitNo procedure recorded
  4. filtrationKeep solid
  5. washNo procedure recorded
  6. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-334adc9550e34d26a2fb40f60da3313b
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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