Tetrahydrofuran → 2,4,6-Trimethyl-N-[2,2,2-trifluoro-1-(6-methyl-3,4-dihydro-2H-quinolin-1-ylmethyl)ethyl]benzenesulfonamide

HRID 96700

Reaction equation

HRID 96700 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][CH2:7][CH2:6][CH2:5]2.[F:12][C:13]([CH:14]1[N:15]([S:17](=[O:18])(=[O:19])[c:20]2[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]2[CH3:26])[CH2:16]1)([F:29])[F:30]>>[CH3:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH2:16][CH:14]([C:13]([F:12])([F:29])[F:30])[NH:15][S:17](=[O:18])(=[O:19])[c:20]1[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]1[CH3:26])[CH2:7][CH2:6][CH2:5]2

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 666786-Methyl-1,2,3,4-tetrahydroquinolineHCID 574740362-Trifluoromethyl-1-(2,4,6-trimethylbenzenesulfonyl)aziridine

Product 1

HCID 115902962,4,6-Trimethyl-N-[2,2,2-trifluoro-1-(6-methyl-3,4-dihydro-2H-quinolin-1-ylmethyl)ethyl]benzenesulfonamide

Sources & evidence

ORD record
ord-5bf9c7a5da0b4779b2b40313e085f419
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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