Glutaric anhydride → Phthalic Acid

HRID 971456

Reaction equation

HRID 971456 reaction equation
N[C:2]1[CH:3]=[C:4]([C:11]([OH:13])=[O:12])[C:5](=[CH:9][CH:10]=1)[C:6]([OH:8])=[O:7].C1(=O)OC(=O)CCC1>O1CCOCC1>[C:11]([OH:13])(=[O:12])[C:4]1[C:5](=[CH:9][CH:10]=[CH:2][CH:3]=1)[C:6]([OH:8])=[O:7]

Participants

4

Reactant 2

HCID 7940Glutaric anhydrideHCID 729124-Aminophthalic acid

Product 1

HCID 1017Phthalic Acid

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

65.1 g (0.36 mol) of 4-aminophthalic acid in 500 ml of dioxane are reacted with 43.12 g (0.38 mol) of glutaric anhydride, in the manner described in Example 9, to give 4-glutaramidyl)-phthalic acid, and the latter is subsequently cyclised. 70 g (75% of theory) of 4-(glutarimidyl)-phthalic anhydride of melting point 220°-222° C. are obtained.

Sources & evidence

ORD record
ord-fec00bd137a440758e615126cce69ed4
Source dataset
uspto-grants-1979_07
Patent number
US04160081

Linked notes

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