Potassium Hydroxide → Ethylene glycol bis[2hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]ether

HRID 972019

Reaction equation

HRID 972019 reaction equation
[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:29][CH:19]1[CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH:26]1[O:28][CH2:27]1.[OH-:30].[K+]>CO>[OH:18][CH:19]([CH2:29][N:6]1[C:5](=[O:30])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH:26]([OH:28])[CH2:27][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 16683Glycol diglycidyl etherHCID 204818537,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

Product 1

HCID 131711583Ethylene glycol bis[2hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]ether

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

10.0 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione, 3.0 g of ethylene glycol bis(2,3-epoxypropyl)ether and 0.1 g of potassium hydroxide were reacted in 60 ml of methanol, following substantially the same procedure as in Example 1. The desired Compound No. 166 was obtained in the form of white crystals, melting at 213°-215° C.

Sources & evidence

ORD record
ord-1a8c848fd0f7414d9307f74c4b6ab85f
Source dataset
uspto-grants-1979_07
Patent number
US04162246

Linked notes

Loading…