Basic information
- CAS
2224-15-9- Standard SMILES
C(COCC1CO1)OCC1CO1- InChIKey
AOBIOSPNXBMOAT-UHFFFAOYSA-N- Molecular formula
- C8H14O4
- Average molar mass
- 174.19 g/mol
Overview
industrial hardener; structure
Names & identifiers
- Preferred name
- Glycol diglycidyl ether
- IUPAC
- 2-[2-(oxiran-2-ylmethoxy)ethoxymethyl]oxirane
- English name
- Ethylene glycol diglycidyl ether
- Molecular formula
- C8H14O4
- Molecular weight
- 174.19
Names & synonyms
Ethylene glycol diglycidyl ether2224-15-9Glycol diglycidyl etherDTXSID4044876Bis(1,2-epoxypropylether)ethanediolOxirane, 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-EX 810Oxirane, 2,2'-(1,2-ethanediylbis(oxymethylene))bis-NSC-547405R860RS597DTXCID2024876EGDGE
Show more names
Ethylene glycol diglycidyl ether1ex810dv1143QUETOL 651Denacol EX 811UNII:5R860RS597
PEODGE polymerRefChem:139138Poly(ethylene oxide) diglycidyl ether218-746-21,2-Bis(2,3-epoxypropoxy)ethane1,2-bis(oxiran-2-ylmethoxy)ethane26403-72-51,2-Bis(glycidyloxy)ethane
Database identifiers
- CAS
2224-15-9、26403-72-5- PubChem CID
- 16683
- ChEMBL
CHEMBL3182506- UNII
- 5R860RS597
- EC Number
- 218-746-2
- Nikkaji
- J116.203I
Properties
Computed structural properties
- XLogP
- -0.7
- Topological polar surface area
- 43.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 7
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 123
Experimental & physicochemical properties
Physical DescriptionLiquid
Collision Cross Section135.8 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4044876]
Physicochemical properties
- Boiling point
- 112 °C4.5 · 112 °C4.5 mm Hg(lit.)
- Density
- 1.118 g/mL · 1.118 g/mL at 25 °C(lit.)
- vapor pressure
- 11.6 · 11.6-82.3Pa at 20-50℃
- refractive index
- 20 · n20/D 1.463(lit.)
- Flash point
- 230 °F · >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C8H14O4/c1(9-3-7-5-11-7)2-10-4-8-6-12-8/h7-8H,1-6H2
- InChIKey
- AOBIOSPNXBMOAT-UHFFFAOYSA-N
- SMILES
- C(OCC1CO1)COCC1CO1
- LogP
- -0.654 at · -0.654 at 20℃
- CAS DataBase Reference
- 2224 · 2224-15-9(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 5 R860RS597 · 5R860RS597
- NIST Chemistry Reference
- Ethylene glycol diglycidyl ether(2224-15-9)
- EPA Substance Registry System
- Ethylene glycol diglycidyl ether (2224-15-9)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319
- Precautionary statements
- 264 · P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazard Codes
- Xi
- Risk Statements
- 38 · 38
- Safety Statements
- 26 · 26-36/37/39
- RIDADR
- 2810 · 2810
- WGK Germany
- 3 · 3
- RTECS
- 5780000 · KH5780000
- F
- 21 · 21
- TSCA
- TSCA listed
- HazardClass
- 6.1 · 6.1(b)
- PackingGroup
- III
- HS Code
- 29109000 · 29109000
- Toxicity
- 50 oral · LD50 oral in rat: 2500uL/kg
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 15.6% (37 of 237) of reports.
Warning
H302 (56.1%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P318, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 237 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-(oxiranylmethyl)-.omega.-(oxiranylmethoxy)-
Oxirane, 2,2'-[1,2-ethanediylbis(oxymethylene)]bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2,2'-[1,2-ethanediylbis(oxymethylene)]bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.
Status: Active Update: 07-08-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/26521
Oxirane, 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesAcute Tox. 4 (56.1%)
Safety data
- F
- 21
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- KH5780000
- ridadr
- 2810
- hs_code
- 29109000
- Toxicity
- LD50 oral in rat: 2500uL/kg
- risk_code
- 38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36/37/39
- hazard_class
- 6.1(b)
- packing_group
- III
- Hazard statements
- H315-H319
- REACH Registrations
- Active
- Precautionary statements
- P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSynthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Uses & manufacturing
U.S. Production2023: <50,000 lb
Industry UsesOther
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Oxirane, 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-: ACTIVE
Applications
UsesEthylene Glycol Diglycidyl Ether is commonly added to asorbants because of it high carbon dioxide absorbing capacity.
Upstream & downstream products
Upstream raw materials
Suppliers25 total
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
上海拓旸生物科技有限公司021-59555769 13524932310 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
江苏豪隆化工有限公司0513-89083520 13328092525 · [email protected]
广东百科试剂有限公司13532366769 13686183698 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
江苏艾康生物医药研发有限公司025-5885952 15955137747 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
启源（广东）医药化工有限公司18026564465 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
湖北鑫杰成化工科技有限公司18008658050 18008658050 · [email protected]
金锦乐(湖南)化学有限公司18001959627(微信同号) 18001959627 · [email protected]
湖北华创源新材料有限公司027-19807233353 19807233353 · [email protected]
河南威梯希化工科技有限公司0371-53732842 13383863444 · [email protected]
嘉兴市德亿化工有限公司86-0573-85866609 18367600069 · [email protected]
上海易恩化学技术有限公司400-400-1332688 18019345275 · [email protected]
天津希恩思生化科技有限公司400-6387771-6039 18920764717 · [email protected]
广东翁江化学试剂有限公司0751-2815688 13927872512 · [email protected]
Aladdin Scientific[email protected]
广东元丰化学试剂有限公司0751-2829979 13318584237 · [email protected]
唐缘生命科学（上海）有限公司400-618-1121 17316483629 · [email protected]
Related reactions
16 records
Compound notes
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