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Isocyanate → HCID 20396691, compound

HRID 972124
Notes
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Reaction equation

HRID 972124 reaction equation
[CH2:1]([O:4][CH:5]([O:15][CH2:16][CH2:17][CH3:18])[CH2:6][S:7][C:8]1[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=1)[CH2:2][CH3:3].[CH:19]1([N:22]=[C:23]=[O:24])[CH2:21][CH2:20]1.[N-]=C=O>C1C=CC=CC=1.C(N(CC)CC)C>[CH:19]1([NH:22][C:23](=[O:24])[O:14][C:11]2[CH:10]=[CH:9][C:8]([S:7][CH2:6][CH:5]([O:4][CH2:1][CH2:2][CH3:3])[O:15][CH2:16][CH2:17][CH3:18])=[CH:13][CH:12]=2)[CH2:21][CH2:20]1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

6

Reactant 3

HCID 105034IsocyanateHCID 637659IsocyanatocyclopropaneHCID 20396643HCID 20396643, compound

Product 1

HCID 20396691HCID 20396691, compound

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 241BenzeneSolvent

Procedure

4-(2,2-Dipropoxyethylthio)phenol (0.05 mole) dissolved in benzene (10 ml) is charged into a glass reaction flask equipped with a mechanical stirrer. Cyclopropylisocyanate (0.06 mole) and triethylamine (3 drops) are then added, and the resulting mixture is stirred at room temperature for a period of about 6 hours. The mixture is then stripped of solvent and unreacted isocyanate to yield the desired product O-[4-(2,2-dipropoxyethylthio)phenyl] N-cyclopropylcarbamate as the residue.

Workup

  1. additionis charged into a glass reaction flask
  2. customequipped with a mechanical stirrer

Sources & evidence

ORD record
ord-64c5e44247944328b0686fce5dd7fad2
Source dataset
uspto-grants-1979_07
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04163112

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes