Benzylamine → N-benzyladamantane-1-carboxamide

HRID 972645

Reaction equation

HRID 972645 reaction equation
[C:1]12([C:11](Cl)=[O:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH2:14]([NH2:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(OCC)C>[CH2:14]([NH:21][C:11]([C:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2)=[O:12])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 989151-Adamantanecarbonyl chloride

Product 1

HCID 3826889N-benzyladamantane-1-carboxamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Dissolve 2.0 g. of (10 mmoles) of 1-adamantane carboxylic acid chloride in 20 ml. of ethyl ether and add to 3.0 ml. (28.0 mmoles) of benzylamine and repeat the process of Example 11 to obtain the product of this example, m.p. 170°-172° C.

Workup

  1. dissolutionDissolve 2.0 g
  2. customto obtain the product of this example, m.p. 170°-172° C.

Sources & evidence

ORD record
ord-d6c8a2c31fbc49df83019c19b0fe4783
Source dataset
uspto-grants-1977_10
Patent number
US04053509

Linked notes

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