Methylamine → 1,3-Dimethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

HRID 974240Notes

Reaction equation

HRID 974240 reaction equation
[CH3:1][C:2]1[C:3](=O)[O:4][C:5]2[CH2:6][CH2:7][CH2:8][C:9](=[O:12])[C:10]=2[CH:11]=1.[CH3:14][NH2:15]>>[CH3:14][N:15]1[C:5]2[CH2:6][CH2:7][CH2:8][C:9](=[O:12])[C:10]=2[CH:11]=[C:2]([CH3:1])[C:3]1=[O:4]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 159242433-Methyl-5,6,7,8-tetrahydro-cumarin-5-one

Product 1

HCID 159242511,3-Dimethyl-7,8-dihydro-2,5(1H,6H)-quinolinedione

Procedure

Prepared analogously to Example 5(b) from 3-methyl- 5,6,7,8-tetrahydro-cumarin-5-one and methanolic methylamine solution a ambient temperature. After evaporation of the methanolic ammonia the residue is recrystallised from water with the addition of charcoal.

Workup

  1. customAfter evaporation of the methanolic ammonia the residue
  2. customis recrystallised from water with the addition of charcoal

Sources & evidence

ORD record
ord-9789afcbb24f479abe2ccd10b42f573e
Source dataset
uspto-grants-1991_11
Patent number
US05068334

Reaction notes

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