Water → 2-Chloro-7-methyl-4-neopentylaminothieno[3,2-d]pyrimidine

Reaction equation

[CH2:13]([C:14]([CH3:15])([CH3:16])[CH3:17])[NH2:18].[Cl:1][c:2]1[n:3][c:4]([Cl:12])[c:5]2[c:6]([n:7]1)[c:8]([CH3:11])[cH:9][s:10]2.[O:20]=[CH:21][N:22]([CH3:23])[CH3:24].[OH2:19]>>[Cl:1][c:2]1[n:3][c:4]([NH:18][CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[c:5]2[c:6]([n:7]1)[c:8]([CH3:11])[cH:9][s:10]2

Participants

Reactant 4

HCID 962Water

HCID 6228Dimethylformamide

HCID 79882Neopentylamine

HCID 71470642,4-Dichloro-7-methylthieno(3,2-d)pyrimidine

Product 1

HCID 183264882-Chloro-7-methyl-4-neopentylaminothieno[3,2-d]pyrimidine

Sources & evidence

ORD record: ord-998f00be7b504dd4a6d38fc7fa400f09
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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