4-Aminobenzoic Acid → 4-[(2-Iodoacetyl)amino]benzoic acid

HRID 97953

Reaction equation

HRID 97953 reaction equation
[Cl:1][CH:2]1[CH:3]([OH:4])[CH:5]([CH2:6][OH:7])[O:8][CH:9]1[n:10]1[c:11]2[n:12][c:13]([NH2:14])[nH:15][c:16](=[O:17])[c:18]2[n:19][cH:20]1.[I:25][CH2:26][C:27](=[O:28])[NH2:29].[I:30][CH2:31][C:32]([O:33][C:34](=[O:35])[CH2:36][I:37])=[O:38].[NH2:39][c:40]1[cH:41][cH:42][c:43]([C:44](=[O:45])[OH:46])[cH:47][cH:48]1.[O:49]1[CH2:50][CH2:51][O:52][CH2:53][CH2:54]1.[P:21]([NH2:22])([O-:23])[O-:24]>>[I:25][CH2:26][C:27](=[O:28])[NH:29][c:40]1[cH:41][cH:42][c:43]([C:44](=[O:45])[OH:46])[cH:47][cH:48]1

Participants

7

Reactant 6

HCID 9784-Aminobenzoic AcidHCID 3727IodoacetamideHCID 312751,4-DioxaneHCID 2733254Iodoacetic anhydrideHCID 10080320PhosphoramiditeHCID 1370321112-amino-9-[3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

Product 1

HCID 2259994-[(2-Iodoacetyl)amino]benzoic acid

Sources & evidence

ORD record
ord-57ec6d22ce414ff28741a9ee5924a39a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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