Hydrochloric Acid → HCID 21283456, compound
Reaction equation
[OH:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH:9]=[C:8](C(O)=O)[S:7][C:6]=2[CH:13]=1.Cl>[Cu].N1C2C(=CC=CC=2)C=CC=1>[OH:1][C:2]1[C:3]([O:14][CH3:15])=[CH:4][C:5]2[CH:9]=[CH:8][S:7][C:6]=2[CH:13]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of the product from Step C (8 g), copper dust (2 g) and quinoline (40 mL) was heated under reflux for two hours. The hot reaction mixture was poured onto crushed ice (200 g), acidified with 6N hydrochloric acid and filtered. The filtrate was washed with saturated sodium chloride solution, dried (Na2SO4) and filtered and the solvent was evaporated in vacuo, leaving 5 g of waxy solid.
Workup
- temperaturewas heated
- temperatureunder reflux for two hours
- additionThe hot reaction mixture was poured
- filtrationfiltered
- washThe filtrate was washed with saturated sodium chloride solution
- dry with materialdried (Na2SO4)
- filtrationfiltered
- customthe solvent was evaporated in vacuo
- customleaving 5 g of waxy solid
Sources & evidence
- ORD record
- ord-0750d33dc94443628a419d9875f38132
- Source dataset
- uspto-grants-1987_05
- Patent number
- US04668697
Reaction notes
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