Malononitrile, benzylidene- → 5-Aminomethyl-6-phenyl-2-thiophen-2-yl-pyrimidin-4-ylamine

HRID 983875

Reaction equation

HRID 983875 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH2:8])=[NH:7].[CH:9](=[C:16]([C:19]#[N:20])[C:17]#[N:18])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[NH2:20][CH2:19][C:16]1[C:17]([NH2:18])=[N:7][C:6]([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)=[N:8][C:9]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 17608Malononitrile, benzylidene-HCID 2781760Thiophene-2-carboximidamide

Product 1

HCID 222206065-Aminomethyl-6-phenyl-2-thiophen-2-yl-pyrimidin-4-ylamine

Procedure

The title compound, MS: m/e=282.8 (M+H+), was prepared from thiophene-2-carboxamidine and 2-benzylidene-malononitrile in analogy to the process described in Example 11 as a solid.

Sources & evidence

ORD record
ord-5849801c80f64fdaa591bd3f024743f2
Source dataset
uspto-grants-2005_03
Patent number
US06867205B2

Linked notes

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