3,5-Dichloroaniline → N-(3,5-dichlorophenyl)alanine n-propyl Ester

HRID 988480

Reaction equation

HRID 988480 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[C:10]([O:15][CH2:16][CH2:17][CH3:18])(=[O:14])[C:11]([CH3:13])=O>>[CH2:16]([O:15][C:10](=[O:14])[C@H:11]([CH3:13])[NH:5][C:4]1[CH:3]=[C:2]([Cl:1])[CH:8]=[C:7]([Cl:9])[CH:6]=1)[CH2:17][CH3:18]

Participants

3

Procedure

Following General Procedure AA above and using 3,5-dichloroaniline (Aldrich) and n-propyl pyruvate (which can be prepared by following General Procedure AO above using n-propanol in place of iso-butanol), the title compound could be prepared.

Sources & evidence

ORD record
ord-f8d53f8ff7e74fc5819b42f2491aa694
Source dataset
uspto-grants-2003_10
Patent number
US06635632B1

Linked notes

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