Tetrahydrofuran → 4-Methyl-1-(thiazol-4-yl)-4-(trimethylsilyloxy)pent-2-yn-1-one
Reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:11][CH2:12][CH2:13][CH2:14][Li:15].[CH3:16][O:17][N:18]([C:19](=[O:20])[c:21]1[n:22][cH:23][s:24][cH:25]1)[CH3:26].[CH3:1][Si:2]([O:3][C:4]([CH3:5])([C:6]#[CH:7])[CH3:8])([CH3:9])[CH3:10]>>[CH3:1][Si:2]([O:3][C:4]([CH3:5])([C:6]#[C:7][C:19](=[O:20])[c:21]1[n:22][cH:23][s:24][cH:25]1)[CH3:8])([CH3:9])[CH3:10]Participants
5
Sources & evidence
- ORD record
- ord-2978279f3a2a470fa7f0e8e3d9c6d381
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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