ヒドロキシルアミン·硝酸塩

Hydroxylammonium nitrate

HCID 10129901CAS 13465-08-2

基本情報

標準SMILES: NO.O=[N+]([O-])O
InChIKey: NILJXUMQIIUAFY-UHFFFAOYSA-N
分子式: H4N2O4
平均分子量: 96.04 g/mol
単同位体質量: 96.01710661

概要

Hydroxylammonium nitrate (HAN) is the salt of hydroxylamine and nitric acid. It is being developed as a potential rocket propellant and is sometimes used in nuclear reprocessing as a plutonium reductant. Nitrite is a toxic compound known to cause methemoglobinemia. (L1137, L1628)

名称と識別子

優先名称: Hydroxylammonium nitrate
IUPAC: hydroxylamine;nitric acid
現地名: ヒドロキシルアミン·硝酸塩
英語名: Hydroxylamine nitrate
分子式: H4N2O4
分子量: 96.04

名称と別名

DTXSID30884613hydroxyazanium nitrateRefChem:1087090DTXCID501024044236-691-213465-08-2Hydroxylammonium nitrateHYDROXYLAMINE NITRATESCHEMBL148735SCHEMBL2359610SCHEMBL9695641SCHEMBL13560600

名称をさらに表示

硝酸ヒドロキシルアンモニウムヒドロキシルアミン·硝酸塩ヒドロキシルアンモニウム硝酸塩硝酸ヒドロキシルアモニウム硝酸ヒドロキシルアミン硝酸ヒドロキシルアミン（別名：ヒドロキシルアミン?硝酸塩）ヒドロキシルアミン・硝酸塩HANhydroxyazanium,nitrateHYDROXYLAMMONIUM OXALATEhydroxylamine,nitrate(salt)Hydroxylamine nitrate solutionHydroxylamine solution nitrateHydroxylammonium nitrate solutionHYDROXYLAMINENITRATE,AQUEOUSSOLUTION

Nitric acid--hydroxylamine (1/1)

データベース識別子

CAS: 13465-08-2
PubChem CID: 10129901
DTXSID: DTXSID30884613
EC Number: 236-691-2

物性

構造計算による物性

極性表面積: 112 Å²
水素結合供与体数: 3
水素結合受容体数: 5
回転可能結合数: 0
重原子数: 6
形式電荷: 0
複雑度: 26.8

実験および物理化学的性質

Chemical ClassesOther Uses -> Explosives

Density1.156 @25 °C

Physical DescriptionAqueous solution; [Sigma-Aldrich MSDS]

物理化学的性質

比重(密度): 1.09 g/mL · 1.09 g/mL at 20 °C
蒸気圧: 9.33 hPa · 9.33hPa at 25℃
水溶解度: 587 g/L · 587g/L at 20℃
LogP: -3.6 · -3.6
CAS データベース: 13465 · 13465-08-2
EPAの化学物質情報: Hydroxylamine nitrate (13465-08-2)

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H201: (Deleted) Explosive; mass explosion hazard [Danger Explosives]

P203, P210, P230, P240, P250, P260, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P370+P380, P372, P373, P391, P401, P405, and P501 (click each P-code to see the statement)

Danger

H201 (100%): (Deleted) Explosive; mass explosion hazard [Danger Explosives]

危険有害性情報

Regulatory InformationStatus: Active Update: 29-04-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6670

Hazards Summary · 1 件

Classifications by the EC: Risk of explosion by shock, friction, fire, or other sources of ignition; Limited evidence of a carcinogenic effect; Toxic in contact with skin; Harmful by ingestion (danger of serious damage to health by prolonged exposure); Irritating to skin and eyes; May cause sensitization by skin contact; [EC: SCCS] A skin and strong eye irritant; May cause CNS depression, respiratory sensitization, and induce methemoglobinemia; Harmful by ingestion; Highly toxic by skin absorption; [Sigma-Aldrich MSDS] See Hydroxylamine. See NITRATES and NITRITES.

Hazard Classes and Categories · 3 件

Expl. 1.1 (100%)

Explosive - division 1.1

Expl. 1.1 ****

安全と保護具

Protective Action Criteria (PAC) · 3 件

0.16 [ppm]

24 [ppm]

92 [ppm]

毒性情報

Treatment · 1 件

Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)

Health EffectsNitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137)

Adverse EffectsMethemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

Exposure RoutesOral (L1137) ; inhalation (L1137)

Toxicity Summary · 1 件

Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613)

Signs and Symptoms · 1 件

Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137)

安全データ

wgk: 3
tsca: TSCA listed
ridadr: 1759
risk_code: 1-22-36/37/38-43-48/22-34-20/21/22-50
hazard_code: Xn,C,Xi,N
safety_code: 26-36/37-45-36/37/39-35-61
hazard_class: 8
packing_group: III

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137)

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