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酢酸銀(I)

Silver acetate

HCID 11246
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基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
563-63-3
標準SMILES
CC(=O)[O-].[Ag+]
InChIKey
CQLFBEKRDQMJLZ-UHFFFAOYSA-M
分子式
AgC2H3O2
平均分子量
166.91 g/mol
単同位体質量
165.9184

概要

Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.

名称と識別子

優先名称
Silver acetate
IUPAC
silver acetate
現地名
酢酸銀(I)
英語名
Silver acetate
分子式
C2H3AgO2
分子量
166.91

名称と別名

Silver acetate563-63-3Silver(I) acetateSilver(1+) acetateSilver monoacetateACETIC ACID, SILVER(1+) SALT19PPS85F9HDTXSID8032041NSC-112212RefChem:183021DTXCID6012041209-254-9
名称をさらに表示
アセトキシ銀(I)酢酸銀(I)酢酸銀酢酸銀(Ⅰ)酢酸銀 PURUM P.A.,≥99.0% (T)酢酸銀 REAGENTPLUS,99%酢酸銀, 99.9%AgOAcsilver acetate, anhydrousver acetateSilver acetatAcetoxysilver(I)Silveracetate,99%silver(1+)acetatesilvermonoacetate
argentio acetatesilver;acetateAcetic acid silver saltAcetic acid, silver(1+) salt (1:1)Acetic acid silver(I) saltSilver acetate Ag(OAc)Argentous acetate; Silver Monoacetate;MFCD00012446

データベース識別子

CAS
563-63-3
PubChem CID
11246
DTXSID
DTXSID8032041
ChEMBL
CHEMBL4464576
UNII
19PPS85F9H
EC Number
209-254-9
Nikkaji
J43.267I

物性

構造計算による物性

極性表面積
40.1 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
0
重原子数
5
形式電荷
0
複雑度
25.5

実験および物理化学的性質

Chemical ClassesMetals -> Organic Acids, Metal Salts
Density3.26 at 68 °F (USCG, 1999) - Denser than water; will sink
Physical Description · 3 件

Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.

Liquid; Other Solid

White to slightly gray solid; Soluble in 100 parts cold water; [Merck Index] Solubility in water = 10 g/L; [ChemIDplus] Beige powder; [Aldrich MSDS]

物理化学的性質

融点
93 · decomposes [STR93]
比重(密度)
3.25 · 3.25
貯蔵温度
30 °C · Store below +30°C.
溶解性
10.2 g/リットル · 10.2g/リットル
外見
粉体・固形
色
白から灰色
比重
3.259 · 3.259
水溶解度
10.2 g/L · 10.2g/L(20℃)
Merck
14 · 14,8505
BRN
3595636 · 3595636
安定性
安定性 安定していますが、光に敏感です。強力な還元剤とは相容れない。
InChI
1S/C2H4O2.Ag/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 4 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: Acetic acid, silver(1+) salt

Acetic acid, silver(1+) salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, silver(1+) salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Silver acetate: Does not have an individual approval but may be used under an appropriate group standard

Health HazardsInhalation of dust irritates nose and throat. Contact with eyes or skin causes irritation. If continued for a long period, ingestion or inhalation of silver compounds can cause permanent discoloration of skin (argyria). (USCG, 1999)
Hazards Summary · 1 件

Sensitive to light; [Merck Index] No evidence of developmental toxicity or teratogenicity in rats dosed by gavage on gestation days 6-19 (even at doses maternally toxic); NOAEL for maternal toxicity was 10 mg/kg/day and 100 mg/kg/day for developmental toxicity; [NTP] Dust is irritating to eyes, nose, and throat; Solid irritates skin and eyes; [CHRIS] Caused effects to metabolism and plasma proteins in 4-day intermittent study of rats (641 mg/kg); [RTECS] A skin and strong eye irritant; May cause argyria; [Aldrich MSDS] See Silver.

Reactive GroupSalts, Basic

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Silver and its compounds can be absorbed via inhalation, while silver compounds can also be absorbed orally and dermally. It distributes throughout the body in the blood, particularily to the liver. Insoluble silver salts are transformed into soluble silver sulfide albuminates, bind to amino or carboxyl groups in RNA, DNA, and proteins, or are reduced to metallic silver by ascorbic acid or catecholamines. Metallic silver is oxidized and may deposit in the tissues, causing arygria. Silver is eliminated primarily in the faeces. (L808)

用途と製造

Uses · 2 件

Used in liquid ammonia (oxidizing agent); [Merck Index] Used in anti-smoking remedies; [EPA REDs] Used as a laboratory reagent and oxidizing agent; [Hawley]

Silver acetate is commonly used as a pesticide. It also produces a repulsive taste when combined with cigarette smoke, so it is used in chewing gum and lozenges to aid the cessation of smoking. (L813)

U.S. Production2023: 37,447 lb
Consumer UsesProcessing aids not otherwise specified
Industry UsesProcessing aids not otherwise specified
General Manufacturing Information · 2 件

All Other Chemical Product and Preparation Manufacturing

Acetic acid, silver(1+) salt (1:1): ACTIVE

応用分野 · 6 件

用途酢酸銀(I)(さくさんぎん いち、英: silver(I) acetate)は、主に農薬として使われる感光性の物質である。タバコの煙と反応して不快臭が生まれるので、禁煙補助のチューインガムに使われている。

用途アクリル繊維染色改良剤,農薬原料。

用途ファインセラミックスの製造原科。

説明Silver acetate is an organic compound with the empirical formula CH3COOAg (or AgC2H3O2). It is a photosensitive, white crystalline solid. It is a useful reagent in the laboratory as a water soluble source of silver lacking an oxidizing anion. It has been used in some antismoking drugs.

関連反応

149 件
反応記録を作成
HRID 4281 の反応式
HRID 4281触媒としてuspto-grants-1988_02
HRID 5392 の反応式
HRID 5392触媒としてuspto-grants-1993_09
HRID 21964 の反応式
HRID 21964触媒としてuspto-grants-1995_06
HRID 26267 の反応式
HRID 26267触媒としてuspto-grants-1979_04
HRID 36039 の反応式
HRID 36039触媒としてuspto-grants-1995_05
HRID 66400 の反応式
HRID 66400触媒としてuspto-grants-1978_12
HRID 67028 の反応式
HRID 67028触媒としてuspto-grants-1982_08
HRID 233062 の反応式
HRID 233062触媒としてuspto-grants-1997_01
1 / 19 ページ

化合物ノート

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このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
その他の操作
ノートを作成反応を作成見積依頼を出す
InChIKey
CQLFBEKRDQMJLZ-UHFFFAOYSA-M
SMILES
CC(O[Ag])=O
CAS データベース
563 · 563-63-3(CAS DataBase Reference)
NISTの化学物質情報
Silver acetate(563-63-3)
EPAの化学物質情報
Silver acetate (563-63-3)

化学的性質

化学的特性Off-White/Brown Crystalline Powder

Reactivity Profile
SILVER ACETATE is freely soluble in dilute nitric acid [Merck]. Can serve as an oxidizing agent.
Air and Water ReactionsSlightly soluble in water.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

安全と保護具

First AidINHALATION: move to fresh air.
Exposure Control and Personal Protection0.01 [mg/m3], inhalable fraction, as Ag (salts)[German Research Foundation (DFG)]
Threshold Limit Values (TLV)0.01 [mg/m3], as Ag (sol. compds.)
Permissible Exposure Limit (PEL)0.01 [mg/m3], as Ag (sol. compds.)
Personal Protective Equipment (PPE)Dust mask; goggles or face shield; protective gloves (USCG, 1999)
Immediately Dangerous to Life or Health (IDLH) · 2 件

10 mg Ag/m3 (NIOSH, 2024)

10.0 [mg/m3], as Ag

毒性情報

Health Effects · 1 件

Silver itself is not toxic to humans, but most silver salts are. In large doses, silver and compounds containing it can be absorbed into the circulatory system and become deposited in various body tissues, leading to argyria, which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Argyria is rare, and although, so far as known, this condition does not otherwise harm a person's health, it is disfiguring and usually permanent. Mild forms of argyria are sometimes mistaken for cyanosis. (L809)

Exposure RoutesOral (L808) ; inhalation (L808) ; dermal (L808)
Toxicity Summary · 1 件

Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disrupting selenium-catalyzed sulfhydryl oxidation-reduction reactions and intracellular ion concentrations, respectively. Silver nanoparticles are believed to disrupt the mitochondrial respiratory chain, causing oxidative stress, reduced ATP synthesis, and DNA damage. (L808, A243, A244, A245, A246)

Signs and Symptoms · 1 件

Exposure to high levels of silver for a long period of time may result in a condition called arygria, a blue-gray discoloration of the skin and other body tissues. Argyria is a permanent effect but does not appear to be harmful to health. Exposure to high levels of silver in the air has resulted in breathing problems, lung and throat irritation, and stomach pains. Skin contact with silver can cause mild allergic reactions such as rash, swelling, and inflammation in some people. (L808)

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

安全データ

F
8
wgk
3
tsca
TSCA listed
rtecs
AJ4100000
ridadr
1759
PRTR法
第1種指定化学物質
hs_code
28432900
risk_code
36/37/38-50
化審法
2-693
hazard_code
Xi,N
safety_code
26-36-37/39-61
hazard_class
9
毒劇物取締法
III
Hazard Classifications
Aquatic Acute 1Eye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス
11 - Combustible Solids

使用In the health field, silver acetate-containing products have been used in gum, spray, and lozenges to deter smokers from smoking. The silver in these products, when mixed with smoke, creates an unpleasant metallic taste in the smoker's mouth, thus deterring them from smoking. Lozenges containing 2.5 mg of silver acetate showed "modest efficacy" on 500 adult smokers tested over a three-month period. However, over a period of 12 months, prevention failed. In 1974, silver acetate was first introduced in Europe as an over-thecounter smoking-deterrent lozenge (Repaton) and then three years later as a chewing gum (Tabmint).

一般的な説明White crystalline plates. Light sensitive. Density 3.26 g / cm3.

調製方法 · 1 件

純化方法Shake it with acetic acid for three days, and the process is repeated with fresh acid. The solid is then dried in a vacuum oven at 40o for 48hours. It has also been recrystallised from water containing a trace of acetic acid, and dried in air. Store it in the dark. [Beilstein 2 IV 112.]

上流・下流製品情報

下流製品

Benzenemethanol, ar-methyl-, acetate酢酸リチウム2-Propanone, 1-(acetyloxy)-3-bromo-1,5-ジアセトキシペンタン酢酸 2-ノニル2-(3-(メトキシカルボニル)フェニル)酢酸プロピルシラントリオールトリアセタート酢酸 5-ブロモインドキシル2,3-ジアセトキシブタン酢酸 インドキシル