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トリフェニルスチビン

Triphenylantimony

HCID 11777
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印刷プレビュー
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
603-36-1
標準SMILES
c1cc[c]([Sb]([c]2ccccc2)[c]2ccccc2)cc1
InChIKey
HVYVMSPIJIWUNA-UHFFFAOYSA-N
分子式
C18H15Sb
平均分子量
353.1 g/mol
単同位体質量
352.02119

概要

Triphenylantimony is a chemical compound of antimony. Antimony is a metallic element with the chemical symbol Sb and atomic number 51. Small amounts of antimony are found in the earth's crust. (L741, L808)

名称と識別子

優先名称
Triphenylantimony
IUPAC
triphenylstibane
現地名
トリフェニルスチビン
英語名
Triphenylantimony
分子式
C18H15Sb
分子量
353.07

名称と別名

Triphenylantimony603-36-1TriphenylstibaneTRIPHENYLSTIBINEStibine, triphenyl-Triphenylantimony(III)Antimony(III)triphenylCCRIS 1300DTXSID4052269NSC 2844EINECS 210-037-6Stibine, triphenyl
名称をさらに表示
トリフェニルアンチモントリフェニルアンチモン(III)トリフェニルスチバントリフェニルアンチモニートリフェニルアンチモニトリフェニルアンチモン, 97%トリフェニルスチビンTrifenylstibinTriphenylstibanriphenylantimonytriphenyl-stibinTriphenyl-stibaneTriphenylstilbineANTIMONY TRIPHENYL
UNII-G1X1263AMMBRN 3608108G1X1263AMMHVYVMSPIJIWUNA-UHFFFAOYSA-NSC-28444-16-00-01198 (Beilstein Handbook Reference)DTXCID8030841RefChem:191896

データベース識別子

CAS
603-36-1
PubChem CID
11777
DTXSID
DTXSID4052269
UNII
G1X1263AMM
EC Number
210-037-6
Nikkaji
J35.350G

物性

構造計算による物性

極性表面積
0 Ų
水素結合供与体数
0
水素結合受容体数
0
回転可能結合数
3
重原子数
19
形式電荷
0
複雑度
202

実験および物理化学的性質

Chemical ClassesMetals -> Metals, Organic Compounds
Vapor Pressure0.00000973 [mmHg]
Physical DescriptionWhite to beige crystalline powder; [PMC MSDS]

物理化学的性質

融点
52 · 52-54 °C(lit.)
沸点
377 °C · 377 °C(lit.)
比重(密度)
1 · 1,434 g/cm3
屈折率
1.6948 · 1.6948
闪点
230 °F · >230 °F
貯蔵温度
30 °C · Store below +30°C.
溶解性
0.001 g/l · <0.001g/l
外見
結晶
色
オフホワイト
比重
1.4343 · 1.4343
水溶解度
不溶性
BRN
3608108 · 3608108
安定性
安定。強力な酸化剤とは相容れない。
InChI
1S/3C6H5.Sb/c3*1-2-4-6-5-3-1;/h3*1-5H;
InChIKey
HVYVMSPIJIWUNA-UHFFFAOYSA-N

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 4 件

Danger

H301 (47.9%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P264, P270, P271, P273, P301+P316, P301+P317, P304+P340, P317, P321, P330, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 167 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Chemical: Stibine, triphenyl-

Antimony triphenyl: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryHarmful by inhalation; Toxic by ingestion; [PMC MSDS] See Triphenylantimony dichloride.
Hazard Classes and CategoriesAcute Tox. 3 (47.9%)

安全と保護具

Threshold Limit Values (TLV)0.5 [mg/m3], as Sb
Permissible Exposure Limit (PEL)0.5 [mg/m3], as Sb
Immediately Dangerous to Life or Health (IDLH)50.0 [mg/m3], as Sb

毒性情報

Treatment · 1 件

Following oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal). Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. (T36)

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Antimony is widely distributed throughout the body. The hair and skin contain the highest levels of antimony. The adrenal glands, lung, large intestine, trachea, cerebellum, and kidneys also contain relatively high levels of antimony. Blood is the main vehicle for the transport of absorbed antimony to various tissue compartments of the body. Antimony is a metal and, therefore, does not undergo catabolism. Antimony can covalently interact with sulfhydryl groups and phosphate, as well as numerous reversible binding interactions with endogenous ligands (e.g., proteins). It is not known if these interactions are toxicologically significant. Antimony is excreted via the urine and feces. Some of the fecal antimony may represent unabsorbed antimony that is cleared from the lung via mucociliary action into the esophagus to the gastrointestinal tract. (L741)

用途と製造

Uses · 2 件

Used as a catalyst; [PMC MSDS]

Breathing air, drinking water, and eating foods that contain antimony. Exposure can also occur through dermal or skin contact (L741).

General Manufacturing InformationStibine, triphenyl-: ACTIVE
応用分野 · 3 件

解説Sb(C6H5)3(353.08).トリフェニルスチビンは,三塩化アンチモンとフェニルグリニャール試薬またはフェニルリチウムとを反応させるか,または三塩化アンチモン,臭化フェニル,および金属ナトリウムの反応で得られる.無色の結晶.融点46~48 ℃,沸点220 ℃(1.3 kPa).d2541.4343.空気中で安定である.有機溶媒に可溶,水に不溶.ハロゲン X2 との反応で(C6H5)3SbX2を生じ,濃硝酸との反応では(m-NO2C6H4)3Sb(NO3)2,濃硫酸では(C6H5)3SbSO4を生じる.抗酸化剤,合金触媒,重金属のリガンドに用いられる.森北出版「化学辞典(第2版)

使用Stibonium salts, cocatalyst in converting trienes to aromatics and hydroaromatics, react with nitricsulfuric acid to give trinitro derivatives, polymerization inhibitor, lubricating-oil additive.

一般的な説明Atomic number of base material: 51 Antimony

調製方法

関連反応

2 件
反応記録を作成
HRID 822976 の反応式
HRID 822976生成物としてTest data from https://doi.org/10.1039/C8SC04228D
HRID 2413319 の反応式
HRID 2413319反応物としてuspto-grants-1985_01

化合物ノート

読み込み中…

このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
その他の操作
ノートを作成反応を作成見積依頼を出す
SMILES
c1ccc(cc1)[Sb](c2ccccc2)c3ccccc3
CAS データベース
603 · 603-36-1(CAS DataBase Reference)
NISTの化学物質情報
Stibine, triphenyl-(603-36-1)
EPAの化学物質情報
Stibine, triphenyl- (603-36-1)
化学的性質 · 1 件

化学的特性Triphenylantimony appears as off-white powder that are stable in air. It is soluble in most organic solvents and slightly soluble in ethanol, but remains insoluble in water. The melting point is 50 °C (within a 46–63 °C range), and the boiling point is 377 °C with decomposition. It is classified as toxic and an irritant.

Health Effects · 1 件

Dermal exposure to antimony can cause antimony spots (papules and pustules around sweat and sebaceous glands). Antimony poisoning can also lead to pneumoconiosis. Alterations in pulmonary function and other effects including chronic bronchitis, chronic emphysema, inactive tuberculosis, pleural adhesions, and irritation can result from inhalation of antimony. Increased blood pressure can also result from antimony poisoning. Myocardial depression, vasodilation and fluid loss may cause shock with hypotension, electrolyte disturbances and acute renal failure. Cerebral oedema, coma, convulsions, and death are possible. (L741)

Exposure RoutesInhalation (L741) ; oral (L741) ; dermal (L741)
Toxicity Summary · 1 件

The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The mechanism of action of antimony remains unclear. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. (T18, L741, A238)

Signs and Symptoms · 1 件

Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. Skin or eye contact can cause pain and redness of the exposed surface. (T64, L741)

Carcinogen ClassificationNo indication of carcinogenicity (not listed by IARC). (L135)

安全データ

wgk
2
tsca
TSCA listed
rtecs
WJ1400000
ridadr
UN 3467 6.1/PG 3
PRTR法
第一種指定化学物質
hs_code
29310095
risk_code
20/22-51/53
化審法
(3)-3436
hazard_code
Xn,N
safety_code
61
hazard_class
6.1(b)
packing_group
III
毒劇物取締法
劇物
Hazard Classifications
Acute Tox. 3 OralAcute Tox. 4 InhalationAquatic Chronic 2
ストレージクラス
6.1D - Non-combustible acute toxic Cat.3toxic hazardous materials or hazardous materials causing chronic effects
危険度評価(NFPA 704基準/消防庁データ)
人的[青]=1

純化方法Recrystallise Ph3Sb from acetonitrile [Hayes et al. J Am Chem Soc 107 1346 1985]. [Beilstein 16 H 891, 16 IV 1198.]

上流・下流製品情報

下流製品

2,6-ジイソプロピルフェノール5'-デオキシ-5-フルオロウリジンセフタジジムスクラロース