Triphenylantimony
603-36-1c1cc[c]([Sb]([c]2ccccc2)[c]2ccccc2)cc1HVYVMSPIJIWUNA-UHFFFAOYSA-NTriphenylantimony is a chemical compound of antimony. Antimony is a metallic element with the chemical symbol Sb and atomic number 51. Small amounts of antimony are found in the earth's crust. (L741, L808)
603-36-1DTXSID4052269安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。
Danger
H301 (47.9%): Toxic if swallowed [Danger Acute toxicity, oral]
P261, P264, P270, P271, P273, P301+P316, P301+P317, P304+P340, P317, P321, P330, P391, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 167 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Chemical: Stibine, triphenyl-
Antimony triphenyl: Does not have an individual approval but may be used under an appropriate group standard
Following oral exposure to antimony, administer charcoal as a slurry (240 mL water/30 g charcoal). Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. (T36)
Antimony is widely distributed throughout the body. The hair and skin contain the highest levels of antimony. The adrenal glands, lung, large intestine, trachea, cerebellum, and kidneys also contain relatively high levels of antimony. Blood is the main vehicle for the transport of absorbed antimony to various tissue compartments of the body. Antimony is a metal and, therefore, does not undergo catabolism. Antimony can covalently interact with sulfhydryl groups and phosphate, as well as numerous reversible binding interactions with endogenous ligands (e.g., proteins). It is not known if these interactions are toxicologically significant. Antimony is excreted via the urine and feces. Some of the fecal antimony may represent unabsorbed antimony that is cleared from the lung via mucociliary action into the esophagus to the gastrointestinal tract. (L741)
Used as a catalyst; [PMC MSDS]
Breathing air, drinking water, and eating foods that contain antimony. Exposure can also occur through dermal or skin contact (L741).
解説Sb(C6H5)3(353.08).トリフェニルスチビンは,三塩化アンチモンとフェニルグリニャール試薬またはフェニルリチウムとを反応させるか,または三塩化アンチモン,臭化フェニル,および金属ナトリウムの反応で得られる.無色の結晶.融点46~48 ℃,沸点220 ℃(1.3 kPa).d2541.4343.空気中で安定である.有機溶媒に可溶,水に不溶.ハロゲン X2 との反応で(C6H5)3SbX2を生じ,濃硝酸との反応では(m-NO2C6H4)3Sb(NO3)2,濃硫酸では(C6H5)3SbSO4を生じる.抗酸化剤,合金触媒,重金属のリガンドに用いられる.森北出版「化学辞典(第2版)
使用Stibonium salts, cocatalyst in converting trienes to aromatics and hydroaromatics, react with nitricsulfuric acid to give trinitro derivatives, polymerization inhibitor, lubricating-oil additive.
一般的な説明Atomic number of base material: 51 Antimony
読み込み中…
化学的特性Triphenylantimony appears as off-white powder that are stable in air. It is soluble in most organic solvents and slightly soluble in ethanol, but remains insoluble in water. The melting point is 50 °C (within a 46–63 °C range), and the boiling point is 377 °C with decomposition. It is classified as toxic and an irritant.
Dermal exposure to antimony can cause antimony spots (papules and pustules around sweat and sebaceous glands). Antimony poisoning can also lead to pneumoconiosis. Alterations in pulmonary function and other effects including chronic bronchitis, chronic emphysema, inactive tuberculosis, pleural adhesions, and irritation can result from inhalation of antimony. Increased blood pressure can also result from antimony poisoning. Myocardial depression, vasodilation and fluid loss may cause shock with hypotension, electrolyte disturbances and acute renal failure. Cerebral oedema, coma, convulsions, and death are possible. (L741)
The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes of the glycogenolysis and gluconeogenesis pathways. The mechanism of action of antimony remains unclear. However, some studies suggest that antimony combines with sulfhydryl groups including those in several enzymes important for tissue respiration. The antidotal action of BAL depends on its ability to prevent or break the union between antimony and vital enzymes. Moreover, the The cause of death is believed to be essentially the same as that in acute arsenic poisoning. (T18, L741, A238)
Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache, vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation exposure. Skin or eye contact can cause pain and redness of the exposed surface. (T64, L741)
純化方法Recrystallise Ph3Sb from acetonitrile [Hayes et al. J Am Chem Soc 107 1346 1985]. [Beilstein 16 H 891, 16 IV 1198.]