Hydrazinecarboxaldehyde (HCID 12229)

名称と識別子

優先名称: Hydrazinecarboxaldehyde
IUPAC: formohydrazide
現地名: ホルモヒドラジド
英語名: Formylhydrazine
分子式: CH4N2O
分子量: 60.06

名称と別名

Formylhydrazine624-84-0HydrazinecarboxaldehydeV1D8X13QFNNSC-72391DTXSID6020642RefChem:141311DTXCID00642210-867-9FormohydrazideFormic acid hydrazideFormic hydrazide

名称をさらに表示

ホルモヒドラジドぎ酸ヒドラジドFormic hydrazine

FormylhydrazideN-FORMYLHYDRAZINEFormhydrazideCarbazaldehydeHydrazine, formyl-Formal hydrazineFormhydrazidFormic acid, hydrazide

データベース識別子

CAS: 624-84-0
PubChem CID: 12229
DTXSID: DTXSID6020642
UNII: V1D8X13QFN
EC Number: 210-867-9
Nikkaji: J1.681K

物性

構造計算による物性

XLogP: -2
極性表面積: 55.1 Å²
水素結合供与体数: 2
水素結合受容体数: 2
回転可能結合数: 0
重原子数: 4
形式電荷: 0
複雑度: 20

物理化学的性質

融点: 52 · 52-57 °C (lit.)
沸点: 90 °C/0.7mmHg · 90°C/0.7mmHg(lit.)
比重(密度): 1.094 · 1.094±0.06 g/cm3(Predicted)
屈折率: 1.484 · 1.4840 (estimate)
闪点: 230 °F · >230 °F
貯蔵温度: -20 °C · Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解性: 2.5 %、透明、無色 · 水: 可溶2.5%、透明、無色
酸解離定数(Pka): 13.65 · 13.65±0.20(Predicted)
外見: 光沢のある結晶フレーク
色: 白い
水溶解度: 溶ける
BRN: 635759 · 635759
InChI: 1S/CH4N2O/c2-3-1-4/h1H,2H2,(H,3,4)
InChIKey: XZBIXDPGRMLSTC-UHFFFAOYSA-N
SMILES: [H]C(=O)NN
CAS データベース: 624 · 624-84-0(CAS DataBase Reference)
NISTの化学物質情報: Formic acid hydrazide(624-84-0)
EPAの化学物質情報: Hydrazinecarboxaldehyde (624-84-0)

化学的性質

化学的特性WHITE SHINY CRYSTALLINE FLAKES

安全と法規制

GHS分類

GHS Classification · 5 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (62%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H336 (35.4%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 79 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (62%)；STOT SE 3 (35.4%)

安全データ

F: 3-8-10
wgk: 3
tsca: TSCA listed
rtecs: LQ8615000
hs_code: 29280000
risk_code: 36/37/38-20/21/22
hazard_code: Xi,Xn
safety_code: 26-36-36/37/39
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス: 11 - Combustible Solids

化学と産業

用途と製造

General Manufacturing InformationHydrazinecarboxaldehyde: ACTIVE

応用分野 · 2 件

用途有機合成用試薬。

使用Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.

調製方法

純化方法Recrystallise it from EtOH and dry it in vacuo. Store below 10o; it may disproportionate on storage to 1,2-diformyl hydrazine and hydrazine. It forms a blue [Cu(CH4N2O)]SO4 salt with CuSO4. [Beilstein 2 H 93, 2 III 127, 2 IV 85.]

上流・下流製品情報

上流原料

エタノール Syrup, NF ギ酸エチル水和物ヒドラジン一水和物メタノール

下流製品

チオカルボヒドラジド 4-アミノ-1,2,4-トリアゾール (S)-[2-(ベンジルオキシ)プロピリデン]ヒドラジンカルボキシアルデヒド 4-(4H-1,2,4-トリアゾール-4-イル)安息香酸 5-(2-クロロフェニル)-1H-テトラゾール 3H-1,3,4-oxadiazole-2-thione 4-(3-Chlorophenyl)-4H-1,2,4-triazole-3-thiol 1-Methylethylidene hydrazine carboxaldehyde 1H-1,2,4-Triazole, 5-(diethoxymethyl)-1,2,4-Triazolo[3,4-b]benzothiazole

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

ホルモヒドラジド

基本情報