2,2,6,6-テトラメチル-4-ピペリドン

2,2,6,6-Tetramethyl-4-piperidone

HCID 13220CAS 826-36-8
部分構造検索類似構造を探す

基本情報

標準SMILES
CC1(C)CC(=O)CC(C)(C)N1
InChIKey
JWUXJYZVKZKLTJ-UHFFFAOYSA-N
分子式
C9H17NO
平均分子量
155.24 g/mol
単同位体質量
155.13101417

名称と識別子

優先名称
2,2,6,6-Tetramethyl-4-piperidone
IUPAC
2,2,6,6-tetramethylpiperidin-4-one
現地名
2,2,6,6-テトラメチル-4-ピペリドン
英語名
Triacetonamine
分子式
C9H17NO
分子量
155.24

名称と別名

Triacetonamine826-36-82,2,6,6-Tetramethyl-4-piperidoneVincubineTempidonTMPoneDTXSID40415272K4430S3XPNSC-16579IKH-19DTXCID2021527RefChem:891346
名称をさらに表示
2,2,6,6-テトラメチル-4-ピペリドン2,2,6,6-テトラメチル-4-ピペリジノントリアセトンアミン2,2,6,6-テトラメチル-4-オキソピペリジン2,2,6,6-テトラメチルピペリジン-4-オンビンクビン２，２，６，６テトラメチル４オキソピペリジンTEMPTAATETRAMETHYLPIPERIDINONETRIACETONEAMINEDL-22,2,6,6-Tetramethylpiperidone2,2,6,6-tetramethyl-4-piperidon
2,2,6,6-tetramethylpiperidone-4-toluene-p-sulfonate212-554-22,2,6,6-tetramethylpiperidin-4-oneTriacetonamin2,2,6,6-Tetramethyl-4-piperidinoneTriacetone amineVincubina2,2,6,6-Tetramethyl-4-oxopiperidine

データベース識別子

CAS
826-36-8
PubChem CID
13220
DTXSID
DTXSID4041527
ChEMBL
CHEMBL117614
ChEBI
CHEBI:177813
UNII
2K4430S3XP
EC Number
212-554-2
Nikkaji
J107D

物性

構造計算による物性

XLogP
0.5
極性表面積
29.1 Ų
水素結合供与体数
1
水素結合受容体数
2
回転可能結合数
0
重原子数
11

実験および物理化学的性質

Melting Point34.9 °C
Physical DescriptionSolid
Dissociation Constants7.9

物理化学的性質

融点
59 · 59-61 °C
沸点
105 · 105-105°C/18mm
比重(密度)
0.9796 · 0.9796 (rough estimate)
屈折率
1.468 · 1.4680 (estimate)
闪点
73 °C · 73°C
貯蔵温度
2 · 2-8°C

化学的性質

化学的特性white crystalline powder

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H290 (77.1%): May be corrosive to metals [Warning Corrosive to Metals]；H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (79.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (20.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (79.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (77.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (20.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (20.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (79.2%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P234, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 192 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2 件

Met. Corr. 1 (77.1%)；Acute Tox. 4 (100%)；Skin Corr. 1B (79.2%)；Skin Irrit. 2 (20.8%)；Skin Sens. 1 (79.2%)；Eye Dam. 1 (77.1%)；Eye Irrit. 2 (20.8%)；STOT SE 3 (20.3%)；Aquatic Chronic 3 (79.2%)

Acute toxicity (Oral) - Category 4；Skin corrosion/irritation - Category 1；Serious eye damage/eye irritation - Category 1；Skin sensitization - Category 1；Specific target organ toxicity - Single exposure - Category 2 (cardiovascular system, nervous system)

法規制情報

Regulatory Information · 2 件

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
2
tsca
TSCA listed
rtecs
TO0127900
hs_code
29333990
risk_code
34-22-36/37/38
化審法
(5)-777

化学と産業

薬理情報

Cellular LocationsCytoplasm；Extracellular

用途と製造

General Manufacturing Information4-Piperidinone, 2,2,6,6-tetramethyl-: ACTIVE
応用分野 · 4 件

用途医薬?農薬中間体原料

用途有機合成原料。

説明Triacetonamine (CAS 826-36-8), also known as 2,2,6,6-tetramethyl-4-piperidone or TAA, is a key intermediate in the synthesis of HALS (hindered amine light stabilisers); Their ability to effectively inhibit polymer degradation by scavenging free radicals is based on their sterically hindered amine functional groups, which are capable of forming stable N-oxides as active intermediates (the Denysov cycle). TAA is also used in the synthesis of pharmaceuticals, piperidine nitroso radicals and pyrrolidone derivatives. For example, the oxidation of TAA or its derivatives yields the corresponding tetramethylpiperidine-N-oxide, namely TEMPO; the latter can be used as a polymerisation inhibitor, molecular weight regulator or oxidation catalyst[2].

使用2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.

上流・下流製品情報

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
河南国生化工有限公司17610068021 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

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