2-アミノ-2-メチル-1,3-プロパンジオール
2-Amino-2-methyl-1,3-propanediol
基本情報
- CAS
115-69-5- 標準SMILES
CC(N)(CO)CO- InChIKey
UXFQFBNBSPQBJW-UHFFFAOYSA-N- 分子式
- C4H11NO2
- 平均分子量
- 105.14 g/mol
- 単同位体質量
- 105.07897859
概要
2-amino-2-methylpropane-1,3-diol is an aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.
名称と識別子
- 優先名称
- 2-Amino-2-methyl-1,3-propanediol
- IUPAC
- 2-amino-2-methylpropane-1,3-diol
- 現地名
- 2-アミノ-2-メチル-1,3-プロパンジオール
- 英語名
- 2-Amino-2-methyl-1,3-propanediol
- 分子式
- C4H11NO2
- 分子量
- 105.14
名称と別名
2-Amino-2-methyl-1,3-propanediol115-69-52-Amino-2-methylpropane-1,3-diolAMPDAminoglycolGentimonAminomethyl propanediol1,3-Propanediol, 2-amino-2-methyl-AmmediolIsobutandiol-2-amine1,1-Di(hydroxymethyl)ethylamine2-Amino-2-methyl-1,3-propandiol
名称をさらに表示
2-アミノ-2-メチル-1,3-プロパンジオールＡＭＰＤ2-アミノ-2メチルプロパン-1，3-ジオール2‐アミノ‐2‐メチル‐1,3‐プロパンジオールAMPD bufferAMPD AmmediolAmmediol, AMPDButanediolaMine
CZ7BU4QZJZDTXSID7059430NSC-6364CHEBI:991RefChem:557559DTXCID8033356204-100-7Pentaerythritol dichlorohydrin
データベース識別子
- CAS
115-69-5- PubChem CID
- 1531
- DTXSID
DTXSID7059430- ChEBI
CHEBI:991- UNII
- CZ7BU4QZJZ
- EC Number
- 204-100-7
- Nikkaji
- J35.183K
物性
構造計算による物性
- XLogP
- -1.8
- 極性表面積
- 66.5 Ų
- 水素結合供与体数
- 3
- 水素結合受容体数
- 3
- 回転可能結合数
- 2
- 重原子数
- 7
- 形式電荷
- 0
- 複雑度
- 51.7
実験および物理化学的性質
Chemical ClassesNitrogen Compounds -> Amino Alcohols, Other
Cosmetics
Cosmetic ingredients (Aminomethyl Propanediol) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Aminomethylpropanediol) -> CIR (Cosmetic Ingredient Review)
Buffering
SpringerMaterials PropertiesFusion temperature
Vapor Pressure0.00654 [mmHg]
Physical Description
Large Crystals; Liquid
Solid; [Merck Index] Colorless crystalline solid; [Aldrich MSDS]
物理化学的性質
- 融点
- 100 · 100-110 °C (lit.)
- 沸点
- 151 °C/10 · 151 °C/10 mmHg (lit.)
- 比重(密度)
- 1.0509 · 1.0509 (estimate)
- 蒸気密度
- 3.63 · 3.63 (vs air)
- 蒸気圧
- 10 mm · ~10 mm Hg ( 152 °C)
- 屈折率
- 1.4754 · 1.4754 (estimate)
- 闪点
- 100 °C · >100°C
- 貯蔵温度
- 30 °C · Store below +30°C.
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Danger
H315 (89%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 228 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Chemical: 1,3-Propanediol, 2-amino-2-methyl-
1,3-Propanediol, 2-amino-2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3-Propanediol, 2-amino-2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: 2-amino-2-methylpropane-1,3-diol (EC: 204-100-7)
2-Amino-2-methyl-1,3-propanediol: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryCauses somnolence, muscle weakness, and coma in oral lethal-dose studies of rabbits; [RTECS] A skin and strong eye irritant; [Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (89%)
毒性情報
Adverse EffectsNeurotoxin - Other CNS neurotoxin
Toxicity Summary
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
化学と産業
用途と製造
Uses
CIR ingredient: Aminomethyl Propanediol
CIR ingredient: Aminomethylpropanediol
Used to make surfactants, vulcanization accelerators, and pharmaceuticals; Also used as a biological buffer, absorbent for acidic gases, and emulsifying agent (cosmetics, mineral oil, leather dressings, textile specialties, and cleaning compounds; Also used in hair sprays and wave sets; [Merck Index]
Leather Tanning and Processing [Category: Industry]
U.S. Production2023: 107,056 lb
Consumer UsespH regulating agent
Industry UsesStabilizing agent
Household ProductsInformation on 1 consumer products that contain Aminomethyl propanediol in the following categories is provided:
Use ClassificationCosmetics -> Buffering
General Manufacturing Information
Paint and Coating Manufacturing
1,3-Propanediol, 2-amino-2-methyl-: ACTIVE
応用分野
用途生化学用緩衝剤、有機合成原料、化粧品原料。
使用A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one.
関連反応
188 件
化合物ノート
読み込み中…