4'-ヒドロキシアセトアニリド

解説解熱鎮痛作用を持つ薬剤。脳内で痛みに関与するシクロオキシゲナーゼ（COX-3）という酵素の働きを阻害する。パラセタモール。化学式C8H9NO2小学館 デジタル大辞泉について 情報 | 凡例

用途アニリン系化合物です。シク ロオキシゲナーゼ（COX）活性を阻害し、プ ロスタグランジン生合成阻害作用を示しま す。

用途アニリン系化合物です。シク ロオキシゲナーゼ（COX）活性を阻害し、プ ロスタグランジン生合成阻害作用を示しま す。

用途有機合成原料。

用途医薬(解熱鎮痛剤)

説明Acetaminophen differs from the nonsteroidal anti-inflammatory agents described in that it is devoid of anti-inflammatory and antirheumatic properties. It was recently shown that acetaminophen, like aspirin, inhibits cyclooxygenase action in the brain and is even stronger than aspirin. On the other hand, the mechanism of analgesic action of acetaminophen is not fully clear, since it acts poorly on peripheral cyclooxygenase.

来歴Acetaminophen was first discovered by H. N. Morse in 1878. Although many studies on its use as an analgesic were performed, it wasn’t until 1950 that it was marketed under the name Triagesic. Today, its most common trade names are Tylenol and Panadol, but a large percentage of its sales are as a generic drug. It is the most commonly used medication for pain and fever in both the United States and Europe. It is on the World Health Organization's List of Essential Medicines.

使用Acetaminophen is widely used as an analgesic and fever-reducing agent. Acetaminophen is designed for moderate analgesia. It is also effective like aspirin and is used in analgesia for headaches (from weak to moderate pain), myalgia, arthralgia, chronic pain, for oncological and post-operational pain, etc.

一般的な説明Odorless white crystalline solid. Bitter taste. pH (saturated aqueous solution) about 6.