基本情報
- CAS
36376-47-3- 標準SMILES
Cc1[nH]cnc1CCN.Cl.Cl- InChIKey
BVJIXYJOFWYOBL-UHFFFAOYSA-N- 分子式
- C6H13Cl2N3
- 平均分子量
- 198.09 g/mol
- 単同位体質量
- 197.0486528
名称と識別子
- 優先名称
- 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochloride
- IUPAC
- 2-(5-methyl-1H-imidazol-4-yl)ethanamine;dihydrochloride
- 現地名
- 5-メチル-1H-イミダゾール-4-エタンアミン·2塩酸塩
- 英語名
- 4-Methylhistamine dihydrochloride
- 分子式
- C6H14Cl2N3
- 分子量
- 199.10146
名称と別名
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrochlorideRefChem:458928664-073-636376-47-32-(4-methyl-1h-imidazol-5-yl)ethanamine dihydrochloride5-Methylhistamine dihydrochloride1H-Imidazole-4-ethanamine, 5-methyl-, dihydrochloride2-(5-methyl-1H-imidazol-4-yl)ethanamine;dihydrochloride4-Methyl Histamine Dihydrochloride5-(2-Aminoethyl)-4-methylimidazole Dihydrochloride2-(4-methyl-1H-imidazol-5-yl)ethanaminedihydrochlorideImidazole, 4-(2-aminoethyl)-5-methyl-, dihydrochloride
名称をさらに表示
5-メチル-1H-イミダゾール-4-エタンアミン·2塩酸塩5-メチルヒスタミン二塩酸塩4-メチルヒスタミン二塩酸塩SKF-715174-Methylhistamine di4-Methylhistamine DiHCl4-METHYLHISTAMINE DIHYDROCHLORIDE4-Methylhistamine (hydrochloride)Methylhistamine dihydrochloride, 4-2-(4-methyl-1H-imidazol-5-yl)ethanamine
4-Methylhistamine (dihydrochloride)MFCD017217965-Methyl-1H-imidazole-4-ethanamine dihydrochloride4-(2-Aminoethyl)-5-methylimidazole dihydrochloride4-Methylhistamine 2HCl4-Methyl Histamine DiHClSCHEMBL94563512-(5-methyl-1H-imidazol-4-yl)ethanamine,dihydrochloride
データベース識別子
- CAS
36376-47-3- PubChem CID
- 215819
- DTXSID
DTXSID80189903- ChEMBL
CHEMBL1411701- EC Number
- 664-073-6
物性
構造計算による物性
- 極性表面積
- 54.7 Ų
- 水素結合供与体数
- 4
- 水素結合受容体数
- 2
- 回転可能結合数
- 2
- 重原子数
- 11
- 形式電荷
- 0
- 複雑度
- 84.4
物理化学的性質
- 融点
- 231 · 231-233℃ (ethanol )
- 貯蔵温度
- Desiccate at RT
- 溶解性
- DMSO（微量、加熱）、メタノール（微量）
- 外見
- 個体
- 色
- ホワイト～ペールベージュ
- 水溶解度
- 50 mM · Soluble to 50 mM in water
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
安全データ
- hazard_class
- IRRITANT
化学と産業
応用分野
説明4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine (dihydrochloride) has the potential for the research of immune-related diseases such as cancer and autoimmune disorders.
使用Histamine H2 receptor agonist, antagonist and antineoplastic agent on the in vitro growth of peripheral blood CFU-GM from normal individuals and HL-60 leukemia cells.
サプライヤー30 社
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Aladdin Scientific[email protected]
上海微佳禾生物科技有限公司17502176150; 17502176150 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
Protheragen-ING+86-15618352007 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
北京博奥森生物技术有限公司
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