CAS 54571-67-4 Sodium Pyrrolidone Carboxylate (HCID 23666346)

基本情報

CAS: 54571-67-4
標準SMILES: O=C1CCC(C(=O)[O-])N1.[Na+]
InChIKey: CRPCXAMJWCDHFM-UHFFFAOYSA-M
分子式: C5H6NNaO3
平均分子量: 151.1 g/mol
単同位体質量: 151.02453733

概要

The CIR Expert Panel concluded that PCA (i.e., 2-pyrrolidone-5-carboxylic acid), calcium PCA, magnesium PCA, potassium PCA, and sodium PCA are safe in cosmetics in the present practices of use and concentration described in this safety assessment. PCA and its salts should not be used in cosmetic products in which N-nitroso compounds can be formed.

名称と識別子

優先名称: Sodium Pyrrolidone Carboxylate
IUPAC: sodium 5-oxopyrrolidine-2-carboxylate
現地名: rac-(R*)-5-オキソピロリジン-2β*-カルボン酸ナトリウム
英語名: 2-Pyrrolidone-5-carboxylic acid sodium salt
分子式: C5H8NNaO3
分子量: 153.11

名称と別名

Sodium PCASodium pyrrolidone carboxylatePCA SodaNalidoneAjidew N-50DL-Sodium pyroglutamateSodium DL-pyroglutamateMonosodium 5-oxoprolineSodium 5-oxo-DL-prolinatesodium dl-pyrrolidonecarboxylate5-Oxo-DL-proline, monosodium saltDL-Proline, 5-oxo-, monosodium salt

名称をさらに表示

ピログルタミン酸ナトリウムrac-(R*)-5-オキソピロリジン-2β*-カルボン酸ナトリウムDL-5-オキソプロリンナトリウム5-オキソ-DL-プロリンナトリウム(±)-5-オキソプロリンナトリウム5-オキソピロリジン-2-カルボン酸ナトリウム2-ピロリドン-5-カルボン酸ナトリウム溶液ナトリウム＝5-オキソピロリジン-2-カルボキシラート2‐ピロリドン‐5‐カルボン酸ナトリウム溶液Sodiumpyroglutamate50wt%solutioninwaterSODIUMPYROGLUTAMINATE5-oxo-dl-prolinmonosodiumsalt(±)-5-Oxoproline monosodium saltProline, 5-oxo-, monosodium saltDL-Proline,5-oxo-,monosodiumsalt5-Oxo-DL-proline monosodium saltSodium 5-oxopyrrolidine-2-carboxylate

物性

構造計算による物性

極性表面積: 69.2 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 1
重原子数: 10
形式電荷: 0
複雑度: 159

実験および物理化学的性質

Cosmetics · 2 件

Cosmetic ingredients (Sodium PCA) -> CIR (Cosmetic Ingredient Review)

Antistatic; Humectant; Skin conditioning

物理化学的性質

沸点: 109 °C · 109 °C
比重(密度): 1.27 · 1.27
蒸気圧: 0.001 Pa · 0.001Pa at 25℃
貯蔵温度: Inert atmosphere,Room Temperature
酸解離定数(Pka): 9.94 · 9.94[at 20 ℃]
外見: 解決
色: 無色～ほぼ無色
LogP: -2.12 at · -2.12 at 22.7℃
EPAの化学物質情報: 5 · Monosodium 5-oxoproline (54571-67-4)

化学的性質

化学的特性clear colorless solution

安全と法規制

GHS分類

GHS Classification · 3 件

This chemical does not meet GHS hazard criteria for 100% (108 of 108) of all reports.

Not Classified

Aggregated GHS information provided per 108 reports by companies from 1 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 3 件

Chemical: Proline, 5-oxo-, sodium salt (1:1)

Status: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23503

Proline, 5-oxo-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to human health

Hazard Classes and CategoriesNot Classified

毒性情報

Toxicity Summary · 2 件

Safe for use in cosmetics, with qualifications

安全データ

tsca: TSCA listed
hs_code: 29339980
safety_code: 24/25

化学と産業

用途と製造

UsesCIR ingredient: Sodium PCA

Household Products · 2 件

Information on 47 consumer products that contain 5-Oxo-DL-proline, monosodium salt in the following categories is provided:

Information on 48 consumer products that contain Sodium PCA in the following categories is provided:

Use ClassificationCosmetics -> Antistatic; Humectant; Skin conditioning

General Manufacturing InformationProline, 5-oxo-, sodium salt (1:1): ACTIVE

サプライヤー44 社

毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]

上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

河北创海生物科技有限公司+86-86-13131129325 · [email protected]

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]

化合物ノート

読み込み中…

rac-(R)-5-オキソピロリジン-2β-カルボン酸ナトリウム