Monostearin (HCID 24699)

名称と識別子

優先名称: Monostearin
IUPAC: 2,3-dihydroxypropyl octadecanoate
英語名: 1,2,3-Propanetriol, homopolymer, isooctadecanoate
分子式: C18H36O2.x(C3H8O3)x
分子量: 0

名称と別名

Glyceryl monostearateMonostearin31566-31-1Glycerin 1-monostearateGlycerin 1-stearateStearin, 1-mono-Stearic acid 1-monoglyceride1-Glyceryl stearatealpha-MonostearinGlyceryl 1-monostearateStearoylglycerolGlycerin monostearate

名称をさらに表示

Polyglycerin-3-triisostearat1,2,3-Propanetriol, homopolymer, isooctadecanoate

3-Stearoyloxy-1,2-propanediolGlycerol alpha-monostearateCerasynt SDMonoglyceryl stearateCefatinDermagineMonelginSedetine

データベース識別子

CAS: 123-94-4、14811-92-8、22610-63-5、31566-31-1、83138-62-9、85666-92-8、91052-47-0
PubChem CID: 24699
DTXSID: DTXSID7029160
ChEMBL: CHEMBL255696
ChEBI: CHEBI:75555
UNII: 258491E1RZ
EC Number: 204-664-4、245-121-1、250-705-4、293-208-8、617-739-5
Nikkaji: J10.136B

物性

構造計算による物性

XLogP: 7.4
極性表面積: 66.8 Å²
水素結合供与体数: 2
水素結合受容体数: 4
回転可能結合数: 20
重原子数: 25
形式電荷: 0
複雑度: 281

実験および物理化学的性質

Density0.97 @25 °C

Solubility · 2 件

insoluble in water; soluble in hot oils, organic solvents

soluble in hot alcohol (in ethanol)

Physical Description · 4 件

Dry Powder; Liquid; Other Solid; Dry Powder; Large Crystals; CBI; Large Crystals; Other Solid; Dry Powder

Large Crystals

White waxy solid; [Merck Index]

white to pale yellow wax-like solid with a mild fatty odour

Collision Cross Section201.2 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID7029160]

物理化学的性質

EPAの化学物質情報: 1 · 1,2,3-Propanetriol, homopolymer, isooctadecanoate (83138-62-9)

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 99.6% (708 of 711) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 708 of 711 companies (only 0.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 711 reports by companies from 5 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 708 of 711 reports by companies.；There are 3 notifications provided by 3 of 711 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

This chemical does not meet GHS hazard criteria for 100% (428 of 428) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 428 of 428 companies. For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 428 reports by companies from 1 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 428 of 428 reports by companies.；There are 0 notifications provided by 0 of 428 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 6 件

Chemical: Octadecanoic acid, 2,3-dihydroxypropyl ester

Chemical: Octadecanoic acid, monoester with 1,2,3-propanetriol

Octadecanoic acid, monoester with 1,2,3-propanetriol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, monoester with 1,2,3-propanetriol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Octadecanoic acid, 2,3-dihydroxypropyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, 2,3-dihydroxypropyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/14699

Status: Active Update: 23-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/2133

Other Safety Information · 2 件

IMAP assessments - Octadecanoic acid, 2,3-dihydroxypropyl ester: Human health tier I assessment

IMAP assessments - Octadecanoic acid, monoester with 1,2,3-propanetriol: Human health tier I assessment；IMAP assessments - Octadecanoic acid, monoester with 1,2,3-propanetriol: Environment tier I assessment

Hazards Summary · 1 件

Intraperitoneal LD50 (mouse) = 200 mg/kg; [RTECS] Product of commerce is a variable mixture of glyceryl monostearate and glyceryl monopalmitate; [Merck Index] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; [Alfa Aesar MSDS]

EPA Safer Chemical · 2 件

Chemical: Glyceryl monostearate； Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.

Hazard Classes and Categories · 3 件

Not Classified

安全と保護具

Protective Action Criteria (PAC) · 3 件

0.66 [mg/m3]

7.2 [mg/m3]

43 [mg/m3]

法規制情報

Regulatory Information · 6 件

Chemical: Octadecanoic acid, 2,3-dihydroxypropyl ester

Chemical: Octadecanoic acid, monoester with 1,2,3-propanetriol

Octadecanoic acid, monoester with 1,2,3-propanetriol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, monoester with 1,2,3-propanetriol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Octadecanoic acid, 2,3-dihydroxypropyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, 2,3-dihydroxypropyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/14699

Status: Active Update: 23-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/2133

安全データ

tsca: TSCA listed

化学と産業

用途と製造

Uses · 1 件

Used as a pharmaceutical aid; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as an emulsifier, firming agent, flavor enhancer, lubricant or release agent, masticatory substance, and texturizer for foods; [FDA]

U.S. Production · 2 件

2023: 4,000,000 - <5,500,000 lb；2022: 7,000,000 - <8,500,000 lb；2021: 7,000,000 - <8,500,000 lb；2020: 5,500,000 - <7,000,000 lb

2023: 125,399 lb；2022: 335,698 lb

Consumer UsesLubricating agent；Dispersing agent；Anti-caking agent；Insulators；Anti-adhesive/cohesive；Processing aids not otherwise specified；Surfactant (surface active agent)；Not Known or Reasonably Ascertainable；Emulsifier；Anti-static agent

Industry UsesAnti-static agent；Not Known or Reasonably Ascertainable；Emulsifier；Plasticizer；Surfactant (surface active agent)；Processing aids not otherwise specified；Lubricating agent；Other；Anti-adhesive/cohesive；Dispersing agent；Anti-caking agent

Household ProductsInformation on 51 consumer products that contain Glyceryl monostearate in the following categories is provided:；• Personal Care

Use Classification · 6 件

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index