ステアリン酸ナトリウム

Sodium Stearate

HCID 2724691CAS 822-16-2

基本情報

標準SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].[Na+]
InChIKey
RYYKJJJTJZKILX-UHFFFAOYSA-M
分子式
C18H35NaO2
平均分子量
306.5 g/mol
単同位体質量
306.25347464

名称と識別子

優先名称
Sodium Stearate
IUPAC
sodium octadecanoate
現地名
ステアリン酸ナトリウム
英語名
Sodium stearate
分子式
C18H35NaO2
分子量
306.45907

名称と別名

SODIUM STEARATE822-16-2Sodium octadecanoateOctadecanoic acid, sodium saltFlexichem BStearic acid, sodium saltProdhygineBonderlube 235Edenor FHTINonsoul sn 15QU7E2XA9TGRhenogran nast 50acmf-ge1858
名称をさらに表示
ステアリン酸ナトリウム17-メチルヘプタデカン酸ナトリウムボンデルルーブ235ナトリウム=ステアラートプロッドヒギンオクタデカン酸ナトリウムフレキシケムBステアリン酸Na脂肪族モノカルボン酸軽金属塩ステアリン酸ソーダステアリン酸ナトリウム, tech. gr.NatriumstearatSodiuM stearatOCTADECANOIC ACID SODIUM SALTflexichembbonderlube235stearatedesodiumSodiumStearate>Stearate (sodium)
Prifer 1634E-470(I)STEARIC ACID, SODIUM SALTDTXSID9027318CHEBI:132109RefChem:6249DTXCID807318212-490-5sodium;octadecanoate

データベース識別子

CAS
822-16-2
PubChem CID
2724691
DTXSID
DTXSID9027318
ChEMBL
CHEMBL1906423
ChEBI
CHEBI:132109
UNII
QU7E2XA9TG
EC Number
212-490-5
Nikkaji
J7.124B

物性

構造計算による物性

極性表面積
40.1 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
16
重原子数
21

実験および物理化学的性質

pHAQ SOLN IS STRONGLY ALKALINE, DUE TO HYDROLYSIS; ALC SOLN IS PRACTICALLY NEUTRAL
OdorSLIGHT, TALLOW-LIKE ODOR
Color/FormWHITE POWDER
Solubility · 2 件

SLOWLY SOL IN COLD WATER OR COLD ALC; FREELY SOL IN HOT SOLVENTS

INSOL IN MANY ORGANIC SOLVENTS

Physical Description · 3 件

Liquid; Dry Powder; Large Crystals; Large Crystals; Dry Powder

White to yellow powder or wax-like substance; Stearates are salts of octadecanoic acid; [ACGIH]

White solid; [Merck Index] White powder; [MSDSonline]

Stability/Shelf LifeAFFECTED BY LIGHT

物理化学的性質

融点
270 °C · 270 °C
比重(密度)
1.07 g/cm3 · 1.07 g/cm3
貯蔵温度
2 · 2-8°C
溶解性
96 %)。 · 水およびエタノールにわずかに溶ける(96%)。
外見
粉
色
白い

化学的性質

化学的特性Sodium stearate, NaC18H35O2, white to off-white powder, soluble, froth or foam upon shaking the water solution (soap), formed by reaction of NaOH and stearic acid (in alcoholic solution) and evaporating. Used as a source of stearate.

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 75.6% (391 of 517) of all reports.

Danger

H315 (19.3%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (19%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 517 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 391 of 517 reports by companies.;There are 5 notifications provided by 126 of 517 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 3 件

Chemical: Octadecanoic acid, sodium salt

Octadecanoic acid, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium stearate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Octadecanoic acid, sodium salt: Human health tier I assessment;IMAP assessments - Octadecanoic acid, sodium salt: Environment tier I assessment
Hazards Summary · 2 件

This TLV Documentation applies only to stearic acid and magnesium, sodium, and zinc stearates. It excludes stearates of other metals. TLV Basis is lower respiratory tract irritation. No acute systemic effects of stearic acid have been reported after ingestion. . . . Sprague-Dawley rats fed stearic acid in their diet at 3000 ppm for 209 days showed 'severe pulmonary infection consisting of tracheobronchitis, lobular pneumonia, lipoid histiocytic response, and abscess formation.' [ACGIH] See Stearic acid.

May cause irritation; [MSDSonline] See STEARATES.

Special Reports · 2 件

THE CHEMICAL & PHYSICAL PROPERTIES (INCLUDING SOLUBILITY IN VARIOUS MEDIA) OF SODIUM STEARATE ARE REVIEWED.[LOWER ES; EXAMINATION OF SODIUM STEARATE SOAP; SOAP PERFUM COSMET 54(DEC) 659 (1981)]

THE EFFECT OF TEMPERATURE ON THE DENSITY & VISCOSITY OF SODIUM STEARATE IS DISCUSSED, ALONG WITH ITS LOW TOXICITY & USES IN A WIDE VARIETY OF FORMULATIONS INCLUDING COSMETICS, LUBRICANTS, POLYMERS & RUBBERS.[LOWER ES; SODIUM STEARATE. PART 2. USES; SOAP PERFUM COSMET 55(FEB) 85 (1982)]

EPA Safer ChemicalChemical: Sodium stearate; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Hazard Classes and Categories · 3 件

Skin Irrit. 2 (19.3%);Eye Dam. 1 (19%)

Serious eye damage/eye irritation - Category 2A;Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 2

Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 3

安全と保護具

Threshold Limit Values (TLV) · 5 件

10.0 [mg/m3], inhalable particulate matter (3 mg/m3 for respirable particulate matter)

10.0 [mg/m3], inhalable particulate matter (3 mg/m3 for respirable particulate matter)

8 hr Time Weighted Avg (TWA): 10 mg/cu m. /Stearates; does not include stearates of toxic metals/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Stearates; does not include stearates of toxic metals/

A4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/

Protective Action Criteria (PAC) · 3 件

0.17 [mg/m3]

1.8 [mg/m3]

11 [mg/m3]

毒性情報

Adverse Effects · 2 件

ACGIH Carcinogen - Not Classifiable.

ACGIH Carcinogen - Not Classifiable.

Toxicity Summary · 2 件

The CIR Expert Panel concluded that the following ingredients are safe in the present practices of use andconcentration described in the safety assessment when formulated to be non-irritating and non-sensitizing, which may be basedon a QRA...Sodium Stearate...

Safe for use in cosmetics, with qualifications

Human Toxicity Excerpts · 2 件

SEE SOAPS. BY INTRAUTERINE INJECTION (AS IN SOME CRIMINAL ABORTIONS), SOAPS CAUSE HEMOLYSIS, EMBOLI, HYPERPYREXIA, SHOCK, RENAL DAMAGE, & OFTEN PROMPT DEATH. /SOAPS/

SEE SOAPS. THEY ARE...LESS LETHAL THAN SYNTHETIC ANIONIC DETERGENTS & EVEN LESS THAN MOST NONIONIC DETERGENTS. HOWEVER, SOAPS WITH APPRECIABLE CONTENT OF FREE ALKALI (EG, SOME LAUNDRY SOAPS) ARE LESS BENIGN. /SOAPS/

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
Non-Human Toxicity Excerpts · 4 件

SEE SOAP. EXPERIMENTAL APPLICATION OF PURE GRANULATED WHITE SOAP TO RABBIT EYES CAUSES A MODERATELY SEVERE REACTION, GRADED 8 ON A SCALE OF 1 TO 10 AFTER 24 HR. ...SIMILARLY 5% SOLN OF SOAP CAUSES TRANSIENT MILD CONJUNCTIVAL HYPEREMIA & OPTICAL IRREGULARITY OF THE CORNEAL EPITHELIUM IF THE EXPOSURE IS BRIEF. /SOAP/

SODIUM STEARATE PRODUCED HYPERTHERMIA WHEN INJECTED INTO THE CEREBRAL VENTRICLES OF CONSCIOUS CATS. THRESHOLD EFFECTS WERE OBTAINED WITH AS LITTLE AS 2.0-5.0 MUG. THE HYPERTHERMIC EFFECT REACHED ITS MAXIMUM 2-3 HR AFTER ADMIN & LASTED FOR MORE THAN 12 HR. THE RISE IN TEMPERATURE WAS ALWAYS ASSOCIATED WITH SEDATION.

CULTURES OF RAT HEART MUSCLE (M) & ENDOTHELIOID (E) CELLS WERE TREATED FOR 30 MINUTES WITH SODIUM STEARATE AT CONCN OF 5X10-6 & 5X10-4 MOLAR & A FREE FATTY ACID (FFA)-TO-ALBUMIN RATIO OF 6:1. SODIUM STEARATE LABILIZED M CELL LYSOSOMES, BUT LYSOSOMES OF E CELLS WERE NOT SIGNIFICANTLY AFFECTED.

SODIUM STEARATE INDUCED PLASMA PLATELET AGGREGATION IN VITRO & THROMBOPENIA IN RABBITS AFTER INJECTION.

Evidence for CarcinogenicityA4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/

法規制情報

Regulatory Information · 3 件

Chemical: Octadecanoic acid, sodium salt

Octadecanoic acid, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium stearate: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
1
tsca
TSCA listed
rtecs
WI4725000
ridadr
3077
hs_code
29157090
化審法
(2)-611, (7)-973 優先評価化学物質

化学と産業

用途と製造

Uses · 6 件

CIR ingredient: Sodium Stearate

Used in cosmetics, pharmaceuticals, food additives, waterproofing agents, plastic stabilizers, emulsifiers, and rubber lubricants and dusting agents; Stearic acid occurs naturally in human and animal fats and oils and in some vegetable oils, including cocoa oil. Stearic acid can be prepared from animal fat (triglyceride) by treating with water at high temperature, leading to hydrolysis of triglycerides, or by hydrogenation of unsaturated vegetable oils such as cottonseed oil. [ACGIH]

Used in pharmaceuticals (emulsifying and stiffening agent); in glycerol suppositories; in toothpastes; as waterproofing agent; as gelling agent; in cosmetics; as stabilizer in plastics; and as topical medication; [HSDB] Used in various cleaning products (most common ingredient in soap); as food additive (binder, emulsifier, and anti-caking agent); [CHEMINFO]

IN GLYCEROL SUPPOSITORIES; ALSO IN TOOTHPASTE; AS WATERPROOFING AGENT; PHARMACEUTIC AID (EMULSIFYING & STIFFENING AGENT)

MEDICATION: HAS BEEN USED TOPICALLY IN SYCOSIS & OTHER SKIN DISEASES

GELLING AGENT; IN COSMETICS; STABILIZER IN PLASTICS

ImpuritiesUSUALLY CONTAINS SODIUM PALMITATE
U.S. Exports(1986) No Data
U.S. Imports(1986) No Data
U.S. Production · 2 件

2023: 5,500,000 - <7,000,000 lb;2022: 7,000,000 - <8,500,000 lb;2021: 7,000,000 - <8,500,000 lb;2020: 5,500,000 - <7,000,000 lb

(1986) No Data

Consumer UsesPolymerization promoter;Lubricating agent;Surfactant (surface active agent);Thickening agent;Emulsifier
応用分野 · 4 件

用途合成ゴムや合成樹脂の乳化重合剤及び分散剤、離型剤、ハミガキ粉、防水剤、無機粉体の表面改質剤、炭カルコーティング剤、アクリルゴム加硫促進剤、化粧品原料(清浄用化粧品、頭髪用化粧品、基礎化粧品、メークアップ化粧品、芳香化粧品、日焼け?日焼け止め化粧品、爪化粧品、アイライナー化粧品、口唇化粧品、口腔化粧品、入浴用化粧品)

用途界面活性剤、洗剤添加物、防水剤。

説明Sodium stearate is the sodium salt of stearic acid. This white solid is the most common soap. It is found in many types of solid deodorants, rubbers, latex paints, and inks. It is also a component of some food additives and food flavorings.

使用sodium stearate is a fatty acid used as a waterproofing agent. Sodium stearate is one of the least allergy-causing sodium salts of fatty acids. It is non-irritating to the skin.

調製方法 · 2 件

Sodium stearate is produced as a major component of soap upon saponification of oils and fats. The percentage of the sodium stearate depends on the ingredient fats. Tallow is especially high in stearic acid content (as the triglyceride), whereas most fats only contain a few percent. The idealized equation for the formation of sodium stearate from stearin (the triglyceride of stearic acid) follows : (C18H35O2)3C3H5 → C3H5(OH)3 + 3 C17H35CO2Na Purified sodium stearate can be made by neutralizing stearic acid with sodium hydroxide.

純化方法It is better to prepare it by adding a slight excess of octadecanoic acid to ethanolic NaOH, evaporating and extracting the residue with dry Et2O. [Beilstein 2 III 1003.]

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

補足説明

定義本品は、ステアリン酸(*)のナトリウム塩であり、次の化学式で表される。参照表示名称:ステアリン酸

定義ChEBI: Sodium octadecanoate is an organic sodium salt comprising equal numbers of sodium and stearate ions. It has a role as a detergent. It contains an octadecanoate.

関連反応

33 件

関連ノート

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