CAS 554-70-1 Triethylphosphine (HCID 27365)

名称と識別子

優先名称: Triethylphosphine
IUPAC: triethylphosphane
現地名: トリエチルホスファン
英語名: Triethylphosphine
分子式: C6H15P
分子量: 118.16

名称と別名

TriethylphosphineTRIETHYLPHOSPHANEPhosphine, triethyl-Triethyl phosphineEINECS 209-068-8UNII-5W435D16PMBRN 09691705W435D16PMPhosphorus triethyl4-16-00-01699 (Beilstein Handbook Reference)TRIETHYLPHOSPHINE [MI]DTXSID3060293

名称をさらに表示

トリエチルホスフィントリエチルホスファントリエチルホスフィン,トルエン溶液トリエチルホスフィン溶液トリエチルホスフィン, 99% (10 wt% in hexanes)トリエチルホスフィン, 99% (20 wt% in ethanol)PEt3Triethylphosphine,99%Et3Ptl409Cytop? 320CYTOP(R) 320AURORA KA-1111HISHICOLIN P-2

CHEBI:39971(C2H5)3Pphosphine, triethylRefChem:191547DTXCID7041885UN2845209-068-8InChI=1/C6H15P/c1-4-7(5-2)6-3/h4-6H2,1-3H

データベース識別子

CAS: 554-70-1
PubChem CID: 27365
DTXSID: DTXSID3060293
ChEBI: CHEBI:39971
UNII: 5W435D16PM
EC Number: 209-068-8
Nikkaji: J44.119H

物性

構造計算による物性

XLogP: 1
極性表面積: 0 Å²
水素結合供与体数: 0
水素結合受容体数: 0
回転可能結合数: 3
重原子数: 7
形式電荷: 0
複雑度: 25

実験および物理化学的性質

Physical DescriptionColorless liquid with an odor of hyacinths; [Merck Index] Pungent odor; [Alfa Aesar MSDS]

物理化学的性質

融点: -88 °C · -88°C
沸点: 127 · 127-128 °C(lit.)
比重(密度): 0.88 g/mL · 0.88 g/mL at 20 °C
屈折率: 20 · n20/D 1.456(lit.)
闪点: 1 °F · 1 °F
外見: 液体
色: 無色
臭い (Odor): 下品で吐き気を催すような悪臭。
水溶解度: 水に不溶。
Merck: 14 · 14,9675
BRN: 969170 · 969170
InChI: 1S/C6H15P/c1-4-7(5-2)6-3/h4-6H2,1-3H3
InChIKey: RXJKFRMDXUJTEX-UHFFFAOYSA-N
SMILES: CCP(CC)CC
CAS データベース: 554 · 554-70-1(CAS DataBase Reference)
NISTの化学物質情報: Phosphine, triethyl-(554-70-1)
EPAの化学物質情報: Phosphine, triethyl- (554-70-1)

化学的性質

化学的特性Colorless Transparent Liquid

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H224 (17.5%): Extremely flammable liquid and vapor [Danger Flammable liquids]；H225 (81.2%): Highly Flammable liquid and vapor [Danger Flammable liquids]；H250 (100%): Catches fire spontaneously if exposed to air [Danger Pyrophoric liquids]；H302 (17.5%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (95%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H318 (17.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P210, P222, P231, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P335+P334, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 80 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazards SummaryPyrophoric; Self-heating in large quantities and may catch fire; An irritant; Harmful by inhalation; [Alfa Aesar MSDS] See Tributylphosphine and tert-Butylphosphine.

Hazard Classes and CategoriesFlam. Liq. 1 (17.5%)；Flam. Liq. 2 (81.2%)；Pyr. Liq. 1 (100%)；Acute Tox. 4 (17.5%)；Skin Corr. 1B (95%)；Eye Dam. 1 (17.5%)

毒性情報

Toxicity DataLC (mouse) > 1,000 mg/m3/10min

安全データ

F: 10-13-23
wgk: 3
tsca: TSCA listed
rtecs: SZ3400000
ridadr: UN 2924 3/PG 2
PRTR法: 1-300
risk_code: 11-34-67-17-40-37-19
安衛法: 有機溶剤中毒予防規則:第2種有機溶剤,57,57-2
消防法: 危-4-1-II
hazard_code: F,C
safety_code: 26-36/37/39-45-7/9-33-16
hazard_class: 4.2
packing_group: I
Hazard Classifications: Acute Tox. 4 OralEye Dam. 1Flam. Liq. 2Pyr. Liq. 1Skin Corr. 1B
ストレージクラス: 4.2 - Pyrophoric and self-heating hazardous materials

化学と産業

用途と製造

UsesUsed in organic syntheses; [Merck Index]

General Manufacturing InformationPhosphine, triethyl-: ACTIVE

応用分野

解説トリエチルホスフィン，三塩化リンとエチルリチウムまたは塩化エチルマグネシウムとの反応によって合成される．無色の液体．沸点127.5 ℃．0.812．1.45799．悪臭を放ち有毒である．有機溶媒に可溶．酸化されやすい．塩化パラジウム，二硫化炭素，三塩化ホウ素などと付加物をつくる．また，低原子価の遷移金属錯体を安定化する配位子として重要である．高分子重合触媒のほか，有機合成試薬として用いられる．

使用Triethylphosphine is used as a ligand for arylation. It is used in organic synthesis.

調製方法 · 1 件

純化方法All operations should be carried out in an efficient fume cupboard because it is flammable, toxic and has a foul odour. Purify the phosphine by fractional distillation at atmospheric pressure in a stream of dry N2, as it is oxidised by air to the oxide. In 300% excess of CS2 it forms Et3PCS2 (m 118-120o crystallising from MeOH) which decomposes in CCl4 to give Et3PS as a white solid m 94o when recrystallised from EtOH. [Sorettas & Isbell J Org Chem 27 273 1962, Henderson & Streuli J Am Chem Soc 82 5791 1960, pK: Henderson & Streuli J Am Chem Soc 82 5791 1960, see also trimethylphosphine.] Store it in sealed vials under N2. Alternatively, dissolve it in Et2O and shake it with a solution of AgI and KI to form the insoluble complex. Filter off the complex, dry it over P2O5 and the Et3P is regenerated by heating the complex in a tube attached to a vacuum system. [Hewitt & Holliday J Chem Soc 530 1953, Schettas & Isbell J Org Chem 27 2573 1962, Kosolapoff Organophosphorus Compounds, Wiley p 31 1950, Beilstein 4 IV 3431.]