Benzyl(methoxymethyl)((trimethylsilyl)methyl)amine (HCID 353442)

名称と識別子

優先名称: Benzyl(methoxymethyl)((trimethylsilyl)methyl)amine
IUPAC: N-(methoxymethyl)-1-phenyl-N-(trimethylsilylmethyl)methanamine
現地名: N-ベンジル-N-(メトキシメチル)-N-トリメチルシリルメチルアミン
英語名: N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
分子式: C13H23NOSi
分子量: 237.41

名称と別名

benzyl(methoxymethyl)[(trimethylsilyl)methyl]amineBenzyl(methoxymethyl)((trimethylsilyl)methyl)amineRefChem:566907630-326-493102-05-7N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamineN-benzyl-1-methoxy-N-((trimethylsilyl)methyl)methanamineN-(methoxymethyl)-1-phenyl-N-(trimethylsilylmethyl)methanamineMFCD00674005N-Benzyl-N-(methoxymethyl)-N-trimethylsilylmethylaminen-methoxymethyl-n-(trimethylsilylmethyl)benzylamineC13H23NOSi

名称をさらに表示

N-ベンジル-N-(メトキシメチル)-N-トリメチルシリルメチルアミンN-[(トリメチルシリル)メチル]-N-(メトキシメチル)ベンゼンメタンアミンN-ベンジル-N-メトキシメチルトリメチルシリルメタンアミンN-(トリメチルシリルメチル)-N-(メトキシメチル)ベンゼンメタンアミン[[ベンジル(メトキシメチル)アミノ]メチル]トリメチルシランN-(メトキシメチル)-N-(トリメチルシリルメチル)ベンゼンメタンアミンN-ベンジル-N-(メトキシメチル)-N-(トリメチルシリルメチル)アミンN-ベンジル-N-(メトキシメチル)トリメチルシリルメタンアミンN-(メトキシメチル)-N-[(トリメチルシリル)メチル]ベンゼンメタンアミンN-(トリメチルシリルメチル)-N-(メトキシメチル)ベンジルアミンN-(メトキシメチル)-N-(トリメチルシリルメチル)ベンジルアミンN‐(メトキシメチル)‐N‐(トリメチルシリルメチル)ベンジルアミンN-メトキシメチル-N-(トリメチルシリルメチル)ベンジルアミンN-(メトキシメチル)-N-(トリメチルシリルメチル)ベンジルアミン, TECH GRADEN-メトキシメチル-N-(トリメチルシリルメチル)ベンジルアミン, 94%ベンジル(メトキシメチル)[(トリメチルシリル)メチル]アミンN-ベンジル-N-メトキシメチル-N-[(トリメチルシリル)メチル]アミンN-ベンジル-1-メトキシ-N-[(トリメチルシリル)メチル]メタンアミンN-[(トリメチルシリル)メチル]-N-(メトキシメチル)ベンジルアミンベンジル(トリメチルシリルメチル)(メトキシメチル)アミンN-Benzyl-N-(methoxymethyl)trimethylsilylmethylamineN-benzyl(methoxy)-N-((trimethylsilyl)methyl)methanamine)-N-trimethyLcas:93102-05-7-N-(methoxymethyLN-(Methoxymethyl)-N-(trimethyl

N-(Methoxymethyl)-N-(trimethylsilylmethyl)-benzylamineN-Benzyl-1-methoxy-N-[(trimethylsilyl)methyl]methanamineS00978F0001-2246N-benzyl-N-methoxymethyl-N-(trimethylsilylmethyl)amineN-benzyl-1-methoxy-N-[(trimethylsilyl)methyl)methanamineN-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amineN-(Methoxymethyl)-N-[(trimethylsilyl)methyl]benzenemethanamine (>90%)

データベース識別子

CAS: 93102-05-7
PubChem CID: 353442
DTXSID: DTXSID30326563
EC Number: 630-326-4
Nikkaji: J436.255A

物性

構造計算による物性

極性表面積: 12.5 Å²
水素結合供与体数: 0
水素結合受容体数: 2
回転可能結合数: 6
重原子数: 16
形式電荷: 0
複雑度: 185

物理化学的性質

沸点: 76 °C0.3 · 76 °C0.3 mm Hg(lit.)
比重(密度): 0.928 g/mL · 0.928 g/mL at 25 °C(lit.)
屈折率: 20 · n20/D 1.492(lit.)
闪点: 151 °F · 151 °F
貯蔵温度: Keep in dark place,Sealed in dry,Room Temperature
溶解性: クロロホルム、酢酸エチルに可溶。
外見: 液体
酸解離定数(Pka): 7.29 · 7.29±0.50(Predicted)
比重: 0.928 · 0.928
色: 無色透明～薄黄色
BRN: 4311216 · 4311216
InChI: 1S/C13H23NOSi/c1-15-11-14(12-16(2,3)4)10-13-8-6-5-7-9-13/h5-9H,10-12H2,1-4H3
InChIKey: RPZAAFUKDPKTKP-UHFFFAOYSA-N
SMILES: COCN(Cc1ccccc1)C[Si](C)(C)C
CAS データベース: 93102 · 93102-05-7(CAS DataBase Reference)

化学的性質

化学的特性N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine is clear colorless to light yellow liquid

安全と法規制

GHS分類

GHS Classification · 5 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (98.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 52 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (98.1%)

安全データ

wgk: 3
ridadr: 1993
hs_code: 29319090
risk_code: 36/37/38
安衛法: 変異原性物質
消防法: 危-4-2-III
hazard_code: Xi
safety_code: 26-37/39
hazard_class: 3
packing_group: Ⅲ
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス: 10 - Combustible liquids

化学と産業

応用分野

用途有機合成原料。

使用N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine is useful reagent in synthesizing N-benzyl substituted pyrrolidines by [3+2] cycloaddition to α,ßunsaturated esters.

調製方法 · 1 件

製造方法most conveniently prepared by treatment of benzylamine with chloromethyltrimethylsilane followed by formaldehyde and methanol.Access to higher ether homologs is achieved by replacing methanol with the appropriate alcohol. An alternate procedure involves alkylation of lithium N-benzyltrimethylsilymethylamide with methoxymethyl chloride.