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酢酸カリウム

Potassium Acetate

HCID 517044
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基本情報名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
127-08-2
標準SMILES
CC(=O)[O-].[K+]
InChIKey
SCVFZCLFOSHCOH-UHFFFAOYSA-M
分子式
C2H3KO2
平均分子量
98.14 g/mol
単同位体質量
97.97701082

名称と識別子

優先名称
Potassium Acetate
IUPAC
potassium acetate
現地名
酢酸カリウム
英語名
Potassium Acetate
分子式
C2H3KO2
分子量
98.14

名称と別名

Potassium acetate127-08-2Diuretic saltACETIC ACID, POTASSIUM SALTAcetic acid, potassium salt (1:1)Potassium ethanoateFEMA No. 2920Octan draselnyKali aceticumPotassium acetatesDTXSID7027043Potassium acetate in plastic container
名称をさらに表示
ジウレト塩酢酸カリウムカリウム=アセタート酢酸カリウム(無水)酢酸カリウム ACS REAGENT,≥99.0%酢酸カリウム PURISS. P.A.,≥99% (過塩素酸 TITRATION)酢酸カリウム PURISS.,MEETS ANALYTICAL SPECIFICATION OF PH. EUR.,BP,E261,99-101%酢酸カリウム REAGENTPLUS,≥99.0%酢酸カリウム 溶液酢酸カリウム (JAN)カリウム アセタート酢酸カリウム, 99.99%KOAcAcOKKacPotassium acetate solutionpharmAcetic acid, potassium salt, 99+%DisalMirfatRusyde
INS NO.261E261INS-261INS-261(I)DTXCID107043E-261M911911U02CHEBI:32029

データベース識別子

CAS
127-08-2
PubChem CID
517044
DTXSID
DTXSID7027043
ChEMBL
CHEMBL1201058
ChEBI
CHEBI:32029
UNII
M911911U02
EC Number
204-822-2、686-264-3
Nikkaji
J2.516J

物性

構造計算による物性補完中

極性表面積
40.1 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
0
重原子数
5
形式電荷
0
複雑度
34

実験および物理化学的性質

pH7,5-9,0 (5 % aqueous solution)
Density · 2 件

1.6 g/cm³

1.57 @25 °C

SolubilitySolubility in water, g/100ml at 20 °C: 256
Melting Point · 2 件

292 °C

309 °C

Physical Description · 4 件

CBI; Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals

Colourless, deliquescent crystals or a white crystalline powder, odourless or with a faint acetic odour

Lustrous colorless or white solid; Rapidly deliquescent; [Merck Index] White crystalline solid; [Aldrich MSDS]

WHITE FLAKES OR CRYSTALLINE POWDER.

物理化学的性質

融点
292 °C · 292 °C
比重(密度)
1.57 g/cm3 · 1.57 g/cm3 at 25 °C (lit.)
蒸気圧
1e-7 hPa · <0.0000001 hPa ( 25 °C)
FEMA
2920 · 2920 | POTASSIUM ACETATE
屈折率
20 · n20/D 1.370
闪点
250 ℃ · >250℃
貯蔵温度
room temp
溶解性

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 87.3% (418 of 479) of all reports.

Warning

H315 (11.5%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (11.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 479 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 418 of 479 reports by companies.;There are 9 notifications provided by 61 of 479 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 4 件

Chemical: Acetic acid, potassium salt

Acetic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15104

Potassium acetate: Non hazardous

Other Safety InformationIMAP assessments - Acetic acid, potassium salt: Human health tier I assessment
Fire Hazards

化学と産業

薬理情報

ATC Code · 2 件

B - Blood and blood forming organs;B05 - Blood substitutes and perfusion solutions;B05X - I.v. solution additives;B05XA - Electrolyte solutions;B05XA17 - Potassium acetate

QB - Blood and blood forming organs;QB05 - Blood substitutes and perfusion solutions;QB05X - I.v. solution additives;QB05XA - Electrolyte solutions;QB05XA17 - Potassium acetate

Mechanism of Action · 1 件

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.

FDA Pharmacological Classification · 4 件

KALI ACETICUM

Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Increased Large Intestinal Motility [PE]; Potassium Salt [EPC]; Potassium Compounds [CS]; Osmotic Laxative [EPC]

POTASSIUM ACETATE

Potassium Compounds [CS]; Osmotic Laxative [EPC]; Increased Large Intestinal Motility [PE]; Potassium Salt [EPC]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]

Absorption, Distribution and ExcretionMostly urine but also skin and feces.

用途と製造

Uses · 3 件

CIR ingredient: Potassium Acetate

Used as a potassium supplement; [Merck Index] Used in the chemical industry (synthesis), textile processing industry, anti-freeze agents, foods (permitted additive in the UK), and pharmaceuticals; Also used as a pH regulator and industrial de-icer; [IUCLID] Used in foods as a buffer and antimicrobial preservative; [JECFA] Used as a dehydrating agent and in crystal glass; [Hawley]

関連反応

4,436 件
反応記録を作成
HRID 1752 の反応式
HRID 1752反応物としてuspto-grants-1998_03
HRID 1753 の反応式
HRID 1753反応物としてuspto-grants-1998_03
HRID 1754 の反応式
HRID 1754反応物としてuspto-grants-1998_03
HRID 1755 の反応式
HRID 1755反応物としてuspto-grants-1998_03
HRID 1756 の反応式
HRID 1756反応物としてuspto-grants-1998_03
HRID 1757 の反応式
HRID 1757反応物としてuspto-grants-1998_03
HRID 1758 の反応式
HRID 1758反応物としてuspto-grants-1998_03
HRID 3415 の反応式
HRID 3415反応物としてuspto-grants-1998_03
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化合物ノート

読み込み中…

このページの内容基本情報名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
その他の操作
ノートを作成反応を作成見積依頼を出す
2 O: · H2O: 1M at20℃、透明、無色
酸解離定数(Pka)
4.756 · 4.756[at 20 ℃]
外見
個体
色
白から薄茶色
比重
1.57 · 1.57
臭い (Odor)
無臭
PH
7.87 · 7.87(1 mM solution);8.33(10 mM solution);8.75(100 mM solution);9.06(1000 mM solution)
由来生物
synthetic
水溶解度
2694 g/L · 2694g/L(25℃)
Merck
14 · 14,7605
BRN
3595449 · 3595449
安定性
安定性 潮解性。安定。強力な酸化剤とは相容れない。
化粧品成分の機能
フィルム形成
InChI
1S/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
InChIKey
SCVFZCLFOSHCOH-UHFFFAOYSA-M
SMILES
[K+].CC([O-])=O
LogP
-3.72 · -3.72
CAS データベース
127 · 127-08-2(CAS DataBase Reference)
NISTの化学物質情報
Potassium acetate(127-08-2)
EPAの化学物質情報
Potassium acetate (127-08-2)

化学的性質

化学的特性酢酸カリウムは化学式でCH3COOKと表される化合物ですこの白い固体は水溶性が高く多くの有機溶媒にも溶ける性質を持っています酢酸のカリウム塩であり食品添加物や農業化学製品さらには医薬品の中間体としても使用されます

化学的特性Potassium acetate, KC2H302, is a white, deliquescent solid, soluble in water and alcohol, insoluble in ether, that melts at 292°C. It is used as an analytical reagent, dehydrating agent, in medicine, and in crystal glass manufacture.

Combustible.
Hazards SummaryA mild skin and eye irritant; [ICSC] Not irritating to eyes of rabbits; [IUCLID] Allowable daily intake (ADI) of not limited [JECFA] May cause irritation; [Aldrich MSDS]
EPA Safer ChemicalChemical: Potassium acetate; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Chemical DangersDecomposes on heating and on contact with strong acids. This produces acetic acid fumes. Reacts violently with strong oxidants. The solution in water is a weak base.
Hazard Classes and Categories · 2 件

Skin Irrit. 2 (11.5%);Eye Irrit. 2 (12.7%);STOT SE 3 (11.5%)

Not Classified

安全と保護具

Fire FightingUse water spray, foam, powder, carbon dioxide.
First Aid Measures · 4 件

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rest.

Safe StorageSeparated from strong acids and strong oxidants.
Spillage Disposal · 1 件

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

Eye PreventionWear safety goggles.
Fire PreventionNO open flames.
Inhalation RiskNo indication can be given about the rate at which a harmful concentration of this substance in the air is reached.
Skin PreventionProtective gloves.
Ingestion PreventionDo not eat, drink, or smoke during work.
Inhalation PreventionUse local exhaust.
Effects of Short Term ExposureThe substance is mildly irritating to the eyes and skin.
Protective Action Criteria (PAC) · 3 件

9.8 [mg/m3]

110 [mg/m3]

640 [mg/m3]

毒性情報

Exposure RoutesThe substance can be absorbed into the body by ingestion.
Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Signs and Symptoms · 2 件

Redness.

Redness.

法規制情報

Regulatory Information · 4 件

Chemical: Acetic acid, potassium salt

Acetic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15104

Potassium acetate: Non hazardous

安全データ

wgk
1
tsca
TSCA listed
rtecs
AJ3325000
毒性
LD50 orally in rats: 3.25 g/kg, H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1969)
hs_code
29159000
hazard_note
Hygroscopic
safety_code
26-24/25
ストレージクラス
13 - Non Combustible Solids
危険度評価(NFPA 704基準/消防庁データ)
人的[青]=0

Textiles (Fiber & Fabric Manufacturing) [Category: Industry];Glass Manufacturing [Category: Industry]

U.S. Production2023: 250,000,000 - <400,000,000 lb;2022: 250,000,000 - <400,000,000 lb;2021: 250,000,000 - <400,000,000 lb;2020: 100,000,000 - <250,000,000 lb
Consumer UsesAnti-scaling agent;Not Known or Reasonably Ascertainable;Soil amendments (fertilizers);Preservative;Flame retardant;Lubricating agent;Other;Anti-freeze agent
Industry Uses · 1 件

Chemical reaction regulator;pH regulating agent;Other;Lubricating agent;Anti-freeze agent;Defoamer;Laboratory chemicals;Intermediate;Preservative;Soil amendments (fertilizers);Catalyst;Corrosion inhibitor;Not Known or Reasonably Ascertainable;Flame retardant

Household ProductsInformation on 3 consumer products that contain Potassium Acetate in the following categories is provided:;• Inside the Home
Use Classification · 5 件

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Food Additives -> ACIDITY_REGULATOR; PRESERVATIVE -> JECFA Functional Classes

Cosmetics -> Film forming

General Manufacturing Information · 2 件

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing;Soap, Cleaning Compound, and Toilet Preparation Manufacturing;Wholesale and Retail Trade;Agriculture, Forestry, Fishing and Hunting;Plastics Material and Resin Manufacturing;Not Known or Reasonably Ascertainable;Construction;All Other Chemical Product and Preparation Manufacturing;Miscellaneous Manufacturing;Food, beverage, and tobacco product manufacturing;All Other Basic Organic Chemical Manufacturing

Acetic acid, potassium salt (1:1): ACTIVE

応用分野 · 9 件

解説酢酸カリウム,サクサンカリウム,CH3COOK(98.14).酢酸を水酸化カリウムまたは炭酸カリウムで中和すると得られる.無色の結晶.融点292 ℃.密度1.57 g cm-3.潮解性で,水にきわめて易溶,エタノール,メタノールに可溶,アセトン,エーテルに不溶.脱水剤,分析試薬,有機合成の原料,クリスタルガラス製造,媒染剤,医薬品(利尿剤)に用いられる.

用途分子生物学研究用。

用途調製液製造原料、医薬品製造原料。

用途医薬品原料、染色助剤、有機合成原料、金属表面処理剤、融雪剤、凍結防止剤。

用途医薬品原料、染色助剤、有機合成原料

説明Potassium acetate (CH3CO2K) is the potassium salt of acetic acid.

使用1) Potassium acetate, crystalline powder, USP is, as its name suggests, the potassium salt of acetic acid and is used as a catalyst for producing polyurethanes2) In the food industry it is used as a food additive, an acidity regulator and a preservative

一般的な説明Potassium acetate is generally used as an acidity regulator, buffer, preservative and firming agent.

使用用途酢酸カリウムは医薬品や凍結防止剤、研究用試薬として使用されている物質です。 その他、酢酸カリウムは分析試薬や脱水剤、消火剤の原料、有機合成の原料など、幅広い用途で使用されている物質です。

調製方法

製造方法Potassium acetate is prepared by addition of potassium carbonate in a small volume of water to acetic acid solution, followed by evaporation and crystallization: K2CO3+ 2CH3COOH →2CH3COOK + H2O

上流・下流製品情報

上流原料

カリウムヒドロキシド酢酸炭酸カリウム

下流製品

桂皮酸1-(4-クロロフェニル)-5-(2-メトキシエトキシ)-4-オキソ-1,4-ジヒドロシンノリン-3-カルボン酸2,2'-[(2β,6β)-1-メチル-2,6-ピペリジンジイル]ビス(1-フェニルエタノン)4-アミノ-3-メトキシフェニルボロン酸, ピナコールエステル3,4-メチレンジオキシけい皮酸5-ブロモインダゾール(4-オキソ-3,4-ジヒドロフタラジン-1-イル)酢酸4-ニトロフェニルボロン酸ribonucleic acid for injectionデオキシコルチコステロン アセタート1-ナフタレン酢酸2,4-ジニトロフェニルヒドラジン5-ヨード-1H-インドール5-ブロモ-4-(トリフルオロメチル)ピリミジン3-(1,3-Benzodioxol-5-yl)-2-propenoyl chloride2,5-ジメトキシテトラヒドロフラン2-(4-ブロモフェニル)チオフェン酢酸エチルエチレン グリコール ジアセタート21-アセチルオキシ-17-ヒドロキシ-16β-メチルプレグナ-1,4,9(11)-トリエン-3,20-ジオン3,4-ジメチルアニリンフェンピクロニル酢酸アリル3-インドール酢酸4-ビニルピリジン2-アミノ-9,9-ジメチルフルオレン酢酸コルチゾン

補足説明

定義ChEBI: A potassium salt comprising equal numbers of potassium and acetate ions