CAS 112-90-3 Oleylamine (HCID 5356789)

概要

promotes fusion of mouse A(9) fibroblasts; RN given refers to parent cpd with unspecified isomeric designation; structure

名称と識別子

優先名称: Oleylamine
IUPAC: (Z)-octadec-9-en-1-amine
現地名: オレイルアミン
英語名: Oleylamine
分子式: C18H37N
分子量: 267.49

名称と別名

OleylamineOleamineOleyl amine112-90-3Armeen OOleinamineNoram OCIS-9-OCTADECENYLAMINEAlamine 11OleylaminKemamine P 9899-Octadecenylamine, (Z)-

名称をさらに表示

オレイルアミン(Z)-9-オクタデセニルアミンノラムOアラミン11(Z)-9-オクタデセン-1-アミン(9Z)-9-オクタデセン-1-アミンアルミーンO[(9Z)-9-オクタデセニル]アミンオレアミンケマミンP-989アロスルフAA-60オレイナミン（Ｚ）９オクタデセン１アミンオレイルアミン, TECH GRADEオレイルアミン, min. 95%オレイルアミン, min. 70%40%9-OCTADECENYLAMINEeyLAO Vnoramoarmeenoalamine11

(Z)-Octadec-9-enylamineZDQ1JWQ8DTNSC-664611-octadeceneamine hydrofluorideoleoylamineRefChem:577369oleylamine phosphate (1:1), (Z)-204-015-5

データベース識別子

CAS: 112-90-3、1838-19-3
PubChem CID: 5356789
DTXSID: DTXSID8026933
ChEMBL: CHEMBL1976606
UNII: ZDQ1JWQ8DT
EC Number: 204-015-5
Nikkaji: J59.382F

物性

構造計算による物性

XLogP: 7.6
極性表面積: 26 Å²
水素結合供与体数: 1
水素結合受容体数: 1
回転可能結合数: 15
重原子数: 19
形式電荷: 0
複雑度: 175

実験および物理化学的性質

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic

CosmeticsAntistatic

Vapor Pressure0.0001 [mmHg]

Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)

Physical Description · 2 件

Liquid; CBI

Liquid; mp = 10-20 deg C; [IUCLID] Light yellow pasty liquid with an amine-like odor (mp = 15-30 deg C); [ECHA] Slightly beige paste; [MSDSonline]

Collision Cross Section180.2 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8026933]

物理化学的性質

融点: 18 · 18-26 °C (lit.)
沸点: 348 · 348-350 °C (lit.)
比重(密度): 0.813 g/mL · 0.813 g/mL at 25 °C (lit.)
蒸気圧: 8 mm · 8 mm Hg ( 135 °C)
屈折率: 20 · n20/D 1.4596(lit.)
闪点: 310 °F · 310 °F
貯蔵温度: Keep in dark place,Inert atmosphere,Room temperature
外見: 液体
酸解離定数(Pka): 10.67 · 10.67±0.10(Predicted)
色: 無色
臭い (Odor): 塩アミン/レモン臭
水溶解度: 不溶性
BRN: 1723960 · 1723960
安定性: 安定。酸、酸塩化物、酸無水物、酸化剤とは混和しません。
化粧品成分の機能: 帯電防止
InChI: 1S/C18H37N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h9-10H,2-8,11-19H2,1H3/b10-9-
InChIKey: QGLWBTPVKHMVHM-MDZDMXLPSA-N
SMILES: [H]\C(CCCCCCCC)=C(/[H])CCCCCCCCN
LogP: 7.78 · 7.780 (est)
CAS データベース: 112 · 112-90-3(CAS DataBase Reference)
EPAの化学物質情報: Oleylamine (112-90-3)

化学的性質

化学的特性beige paste or powder

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P270, P271, P273, P280, P301+P316, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P330, P331, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for 3.7% (60 of 1620) of reports.

Danger

H302 (90.6%): Harmful if swallowed [Warning Acute toxicity, oral]

危険有害性情報

Regulatory Information · 3 件

Chemical: 9-Octadecen-1-amine, (Z)-

9-Octadecen-1-amine, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecen-1-amine, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Oleyl amine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Primary aliphatic (C12-22) and fatty amines: Human health tier II assessment

Hazards Summary · 1 件

Concentrations of 1.5% and 3% in corn oil produced moderate to severe skin irritation in rats; Post-implantation mortality observed in mice following single oral dose on ninth day of pregnancy; No evidence of teratogenicity in rats or rabbits at gavage doses maternally toxic; No evidence of mutagenicity; [IUCLID] Corrosive to rabbit skin; Effects in 28-day gavage study with rats include abnormal gait, decrease in weight gain, and minor toxicity to the liver and kidneys; No histopathological effects observed in reproductive organs; No evidence of mutagenicity, teratogenicity, or developmental toxicity; [ECHA] Causes burns; Harmful by ingestion, inhalation, and skin absorption; Inhalation can cause corrosive effects on the upper respiratory tract and lungs; [Aldrich MSDS]

DOT Hazard Classification · 2 件

Oleylamine

Marine pollutant

Hazard Classes and Categories · 4 件

Acute Tox. 4 (90.6%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Acute Tox. 4

毒性情報

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

TSCA Test Submissions · 1 件

The mutagenicity of (Z)-9-octadecenylamine (ODA) was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537 and TA1538, both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on preliminary bacterial toxicity determinations, ODA, diluted with acetone, was tested for mutagenicity at concentrations up to 20 ug/plate for nonactivated cultures and concentrations up to 200 ug/plate for activated cultures using the plate incorporation method. ODA did not cause a positive response in any of the bacterial tester strains, either with or without metabolic activation.

安全データ

wgk: 2
tsca: TSCA listed
rtecs: RG4130000
ridadr: UN 2735 8/PG 2
毒性: LD50 intraperitoneal in mouse: 888mg/kg
hs_code: 29215900
risk_code: 34-22-50/53
化審法: (2)-133, (2)-185, (2)-176 優先評価化学物質
消防法: 危-4-3-III
hazard_code: C,N
safety_code: 26-36/37/39-45-24/25
hazard_class: 8
packing_group: III
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Asp. Tox. 1Eye Dam. 1Skin Corr. 1BSTOT RE 2STOT SE 3
ストレージクラス: 8A - Combustible corrosive hazardous materials
有毒物質データの: 112-90-3(Hazardous Substances Data)

化学と産業

用途と製造

Uses · 6 件

Used as an intermediate, surfactant in textile production, and cosmetic ingredient; Amine and organic salts: Used as petroleum product and lubricant additives, corrosion inhibitors (i.e. in oil fields), ore flotation reagents, wetting agents for asphalt, and emulsifiers; [HSDB] Used in the EU as intermediate, flotation agent for metals, lubricant in metal processing, fuel additive, corrosion inhibitor, and antistatic agent for paints; [ECHA]

Petroleum Production and Refining [Category: Industry]

...SERIES OF PRIMARY, SECONDARY, & ALIPHATIC AMINES, ORG SUBSTITUTED AMMONIA DERIV.../USED AS/ CORROSION INHIBITORS, ORE FLOTATION AGENTS, TEXTILE FINISHING AGENTS, ASPHALT ANTISTRIPPING AGENTS, RUBBER COMPOUNDING, COLOR PARTICLE DISPERSION, PETROLEUM PRODUCT ADDITIVES, CHEMICAL INTERMEDIATES /ALAMINE/

...SERIES OF STRAIGHT CHAIN AMINES...FROM C12 THROUGH C22... /WHICH/ ARE STRONGLY HYDROPHOBIC & ARE BIODEGRADABLE. .../USED AS/ CATIONIC INTERMEDIATES; REMOVAL OF MOISTURE FROM SURFACES /KEMAMINES/

CHEM INT FOR QUATERNARY AMMONIUM SALTS

CHEM INT FOR OLEYL DIAMINE & ETHOXYLATED OLEYLAMINE

U.S. Exports · 2 件

(1979) No Data

(1981) No Data

U.S. Imports · 2 件

(1979) No Data

(1981) No Data

U.S. Production · 3 件

2023: 8,500,000 - <10,000,000 lb

(1979) 2.24X10+9 GRAMS

(1981) 2.49X10+9 GRAMS

Consumer UsesOther

Industry UsesIntermediate

応用分野 · 4 件

用途有機合成原料。

用途防錆剤、浮遊選鉱剤、繊維仕上げ剤、アスファルト剥離防止剤などの中間原料

使用Oleylamine is a long-chain primary alkylamine broadly used in the synthesis of metallic nanostructures. A variety of metallic nanostructures including Au, Ag, Pt, Pd, and their alloy has been synthesized in the presence of oleylamine. It has several important functions in the synthesis of metallic nanostructure. Oleylamine can simultaneously function as a solvent for the reaction mixture and stabilizing agent for metallic nanostructures. In addition, oleylamine has a boiling point of 364 °C; therefore, it can be used to synthesize metallic nanostructures at high temperatures.

一般的な説明Oleylamine (OAm) is a long chain primary alkyamine, that acts as an electron donor at elevated temperatures. OAm exhibits affinity to metals through NH2 functional groups. FTIR spectra of OAm has been reported. Oleylamine acts as strong reducing agent as well as a stabilizer in the synthesis of nanoparticle.